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All Journal Jurnal Ilmu Kedokteran dan Kesehatan Indonesia
Pramesti Aldelia
Universitas Muhammadiyah Sumatera Utara
Health Professions Public Health

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Pengaruh Minyak Jelantah yang Terkontaminasi Plastik terhadap Kadar Profil Lipid pada Tikus Putih (Rattus novergicus) Pramesti Aldelia; Isra Thristy
Jurnal Ilmu Kedokteran dan Kesehatan Indonesia Vol. 6 No. 3 (2026): Jurnal Ilmu Kedokteran dan Kesehatan Indonesia
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jikki.v6i3.13093

Abstract

Used cooking oil is cooking oil that has been used repeatedly. Used cooking oil may be contaminated with plastic, particularly in unhygienic cooking practices. This contamination has the potential to produce harmful compounds that affect health, including the body’s lipid profile. This study aims to analyse the effect of administering plastic-contaminated used cooking oil on the levels of total cholesterol, triglycerides, HDL and LDL in white rats (Rattus norvegicus). This research method employed an experimental design using a ‘post-test only’ control group approach. A total of 28 white rats were divided into four groups: a negative control group, a positive control group, and two treatment groups receiving plastic-contaminated waste cooking oil at doses of 1 ml/day and 1.5 ml/day, respectively. The treatment was administered for 14 days, followed by blood sampling for lipid profile analysis using spectrophotometric methods. The results of the study showed that the administration of plastic-contaminated used cooking oil significantly increased triglyceride levels (p<0.05), with the highest levels observed in the 1.5 ml/day treatment group. However, no significant effect was found on total cholesterol, HDL and LDL levels (p > 0.05). It was concluded that plastic-contaminated used cooking oil has the potential to significantly increase triglyceride levels, but does not significantly affect total cholesterol, HDL and LDL levels.
Co-Authors Isra Thristy