<![CDATA[Managing type 2 diabetes mellitus involves long-term treatment and regular monitoring to keep blood glucose levels under control. Consistent use of prescribed medication is one aspect that may be related to the achievement of glycemic targets. However, the findings reported in earlier studies have not shown a completely uniform pattern. This review aimed to examine the available evidence concerning the association between patients’ adherence to antidiabetic medication and their glycemic control. Relevant publications were identified through searches conducted in Google Scholar, PubMed, ScienceDirect, and Scopus. The literature search focused on the terms “type 2 diabetes mellitus,” “medication adherence,” and “glycemic control.” The identification, screening, and selection of studies followed the PRISMA framework. After applying the predetermined eligibility criteria, A total of 12 articles published between 2020 and 2025 were retained for analysis from 14,467 records initially identified. Evidence from most of the selected studies demonstrated a statistically significant association between adherence to medication and glycemic outcomes. Across these studies, patients who took their prescribed medication more consistently tended to have better blood glucose or HbA1c results than those with less consistent adherence. The reviewed evidence suggests that maintaining medication adherence is associated with better glycemic control in individuals with type 2 diabetes mellitus. Supporting adherence can involve several approaches, including strengthening patients’ understanding of treatment, increasing support from family members, and providing continued assistance from healthcare professionals.]]>
