Background: Hypertension is one of the most common non-communicable diseases and remains a major global health problem. Uncontrolled blood pressure may increase the risk of cardiovascular complications. Non-pharmacological nursing approaches, including Progressive Muscle Relaxation (PMR) and Slow Deep Breathing (SDB), are commonly incorporated as complementary relaxation techniques in hypertension management. Objective: This case study aimed to describe observed blood-pressure changes and patient responses during a four-week combined intervention of Progressive Muscle Relaxation (PMR) and Slow Deep Breathing (SDB) in a patient with hypertension. Methods: This descriptive single-patient case study involved a 57-year-old patient with hypertension who was selected through purposive sampling. The patient receved a combined PMR and SDB intervention twice weekly for four weeks, resulting in eght sessions. Each combined intervention session lasted 30 minutes and was conducted at 4:00 PM. Blood pressure was measured before and after each session using a digital sphygmomanometer, with the patient in a sitting position after a 5-minute rest period. Measurements were performed at the same time of day for each session. The patient routinely took amlodipine 10 mg once daily at 9:00 PM and continued the medication throughout the intervention period. Results: Across eght sessions, systolic blood pressure decreased by 5–22 mmHg and diastolic blood pressure decreased by 3–15 mmHg between pre- and post-session measurements, with mean reductions of 11.4 mmHg and 7.0 mmHg, respectively. The magnitude of blood-pressure changes varied across sessions. The patient reported feeling more relaxed and comfortable after the intervention sessions and continued routine antihypertensive medication throughout the intervention period. Conclusion: This case demonstrated repeated short-term reductions in blood pressure following combined PMR and SDB sessions in one patient with hypertension. However, the absence of a comparator or untreated period, together with continued antihypertensive medication, limits attribution of the observed blood-pressure changes to the combined intervention. Further studies with larger controlled samples, standardized blood-pressure measurement, medication and lifestyle monitoring, and longer follow-up are needed to evaluate sustained blood-pressure changes