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All Journal Segara Widya: Jurnal Penelitian Seni Health & Medical Sciences
Trisna Sumadewi, Komang
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Arts Dentistry Health Professions Medicine & Pharmacology Nursing Public Health

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Deskripsi Kecerdasan Spasial Visual pada Anak Jalanan Melalui Metode Menggambar Yupardhi, Toddy; Trisna Sumadewi, Komang
Segara Widya : Jurnal Penelitian Seni Vol. 13 No. 1 (2025)
Publisher : Institut Seni Indonesia Bali

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31091/sw.v13i1.3170

Abstract

Kemampuan spasial visual bagi anak jalanan diyakini akan dapat membantu mereka mengembangkan potensi diri dan berkontribusi lebih bagi masyarakat. Penelitian ini bertujuan untuk mendeskripsikan bagaimana kondisi kecerdasan spasial visual anak jalanan yang berada pada naungan Yayasan Bali Street Mums and Kids Denpasar. Metode penelitian menggunakan pendekatan kualitatif yang disajikan secara deskriptif. Metode menggambar dengan dan tanpa instruksi digunakan untuk menganalisis bagaimana deskripsi kecerdasan spasial pada objek kasus. Variabel penilaian berupa tingkat kesesuaian dengan komposisi, proporsi dan teknik perspektif objek. Melalui hasil penelitian ditemukan bahwa anak jalanan pada rentang usia 0-7 tahun cenderung lebih banyak menggunakan imajinasinya dalam memvisualkan objek, sehingga lemah dalam proporsi dan detail, serta belum mengetahui tentang kedalaman objek. Rentang usia 8-12 tahun lebih mendetail dalam menggambar dengan instruksi, sudah lebih proporsional dan mengenal kedalaman objek,  namun kurang dalam memvisualkan imajinasinya. Rentang usia 13-16 tahun menunjukkan variasi yang lebih tinggi antara yang sudah mampu dan yang belum mampu memvisualkan dengan baik sehingga faktor keterampilan menggambar menjadi faktor yang berpengaruh. Penguatan kecerdasan spasial visual agar difokuskan pada rentang usia 8-12 tahun.
The Role of GFAP as a Marker of Astrocyte Activation in the Pathogenesis of Alzheimer's Dementia: A Literature Review Trisna Sumadewi, Komang
Health & Medical Sciences Vol. 3 No. 1 (2025): November
Publisher : Indonesian Journal Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47134/phms.v3i1.519

Abstract

This study aims to comprehensively review the role of glial fibrillary acidic protein (GFAP) as a marker of astrocyte activation in Alzheimer's disease (AD). The research utilized a descriptive-qualitative literature review approach by analyzing various current scientific sources, including indexed international journal articles, research reports, and relevant academic documents published between 2015 and 2025. Data collection involved systematic literature search techniques, followed by analysis comprising theme identification, data reduction, concept categorization, and inductive conclusion drawing to obtain a holistic understanding of the phenomenon under study. The study results show that GFAP plays a crucial role as a sensitive biomarker for astrocyte activation that occurs since the preclinical phase of Alzheimer's, demonstrating a strong correlation with amyloid-beta accumulation and the neuroinflammatory process. In addition to its function in early detection, GFAP is also capable of predicting the conversion of mild cognitive impairment (MCI) to Alzheimer's dementia with high diagnostic accuracy. Despite limitations in specificity and measurement variation, the integration of GFAP with other biomarkers such as pTau, NfL, and YKL-40 significantly enhances diagnostic validity and its potential for therapy monitoring. In conclusion, GFAP is a multifunctional biomarker that not only deepens our understanding of the mechanisms of reactive astrocytosis in AD pathogenesis but also provides new directions for the development of non-invasive diagnostics and more precise therapeutic strategies in neurodegenerative diseases.
Co-Authors Yupardhi, Toddy