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All Journal Biomedical Journal of Indonesia Madani: Multidisciplinary Scientific Journal
Marsasi, Bina
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COMPARISON BETWEEN BELUNTAS (PLUCHEA INDICA LEES) FRACTION AND KETOCONAZOLE INVITRO ON CANDIDA ALBICANS Marsasi, Bina; Yuwono, Yuwono; Salni, Salni
Biomedical Journal of Indonesia Vol 5, No 1 (2019)
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bji.v5i1.7974

Abstract

Beluntas leaves are useful as a treatment for flour albus and discharge caused by fungi. This study aims to find the anti-fungal activity of fraction of beluntas (Pluchea indica Lees) leaf extract against Candida albicans. This research is an in vitro experimental study using the Posttest-only Control Group Design study design. Methanol extract is obtained through maceration process while the fraction is through liquid-liquid fractionation. The most active fraction is determined by the antifungal activity test. The most active fractions with concentrations of 10%, 5%, 2.5%, 1.25%, 0.625% and the diameter of the inhibition zone 0.3125% were measured by the liquid dilution method. Equivalence with drugs is assessed through regression analysis, then the class of active compounds is determined through bioautographic testing using thin layer chromatography. The research results obtained methanol-fraction-water can inhibit the growth of Candida albicans while the methanol extract, n-hexane and ethyl acetate do not inhibit. The methanol fraction of water which has inhibition zone diameters starts at a concentration of 0.3125% with an average diameter of 7.34 mm and at a concentration of 10% the largest diameter of 17.10 mm is obtained. Through the diluent liquid and the KHM solid fraction from the methanol-water fraction is inhibited at a concentration of 0.3125%. Equivalence test shows that 1 mg / ml of ketoconazole is equivalent to 39,561 mg / ml of methanol-water fraction of beluntas leaves. Compounds that inhibit fungi are thought to be active groups of flavonoid and alkaloid compounds. The methanol-water fraction of beluntas leaves (Pluchea indica Lees) has antifungal activity against Candida albicans in vitro.
Faktor yang Mempengaruhi Kunjungan Ibu Hamil Usia 28 Minggu di PMB Bina Marsasi Palembang Tahun 2024 Marsasi, Bina; Julia, Dina; Qur’andini, Dalinur; Magumi, Novita
Madani: Jurnal Ilmiah Multidisiplin Vol 3, No 2 (2025): March
Publisher : Penerbit Yayasan Daarul Huda Kruengmane

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5281/zenodo.14836358

Abstract

Antenatal care (ANC) is monitoring the pregnancy to determine the general health of the mother, enforce accompanying disease early pregnancy, complications of pregnancy and pregnancy risks set. The purpose of this study to determine the factors that affect the visit pregnant women age ? 28 weeks at the PMB Bina Marsasi Palembang type of research used in this study is the author of analytic cross sectional survey. The population in this study were all pregnant women checkups in March 14 to April 2024 samples in this study were 30 pregnant women, based on the results of the univariate analysis of the 30 respondents, visit pregnant women good as many as 20 people (66.7%) and less visits as many as 10 people (33.3%), age at risk as many as 6 people (20%) and the ideal age as many as 24 people (80%), higher education as much as 17 people (56.7%) and low education were 13 persons (43.3%), high parity of 7 people (23.3%) and low parity as many as 23 people (76.7%), good knowledge of as many as 26 people (86.7%) and lack of knowledge as much as 4 people (13.3%), while the results of the bivariate analysis with the chi-square test p = 0.674 obtained> ? = 0.05 means that there is no relationship of age to visit pregnant women, p = 0.446> ? = 0.05 means that there is no relationship of education to visit, p = 0.571> ? = 0.05 means no parity relation to the visit, and p = 0.95> ? of 0.05 indicates no relationship to the knowledge of pregnant women visit . PMB Bina Marsasi can further enhance pemverian information to all pregnant women in the PMB Bina Marsasi about the importance of prenatal care. So that all pregnant women understand the benefits and danger signs during pregnancy.
Co-Authors Julia, Dina Magumi, Novita Qur’andini, Dalinur Salni Yuwono Yuwono