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All Journal Kesmas Indonesia: Jurnal Ilmiah Kesehatan Masyarakat Indonesian Journal of Global Health research
Wijayanti, Siwi Pratama Mars
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Education Health Professions Languange, Linguistic, Communication & Media Nursing Public Health

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The Natural Rodenticidal Effect of Papain Papaya (Carica papaya L.) in Histopathological Changes of Albino Mice Organs Pramestuti, Nova; Sianturi, Corry Laura Junita; Lestari, Eva; Wijayanti, Siwi Pratama Mars
Kesmas Indonesia: Jurnal Ilmiah Kesehatan Masyarakat Vol 11 No 2 (2019): Jurnal Kesmas Indonesia
Publisher : Jurusan Kesehatan Masyarakat dan Fakultas Ilmu-Ilmu Kesehatan Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (653.386 KB) | DOI: 10.20884/1.ki.2019.11.2.1636

Abstract

Reports on the rodenticide effect of papain papaya to control rats and mice is scarce. The aim of this study was to determine pathological changes in  albino mice internal organs (gaster, kidney, liver and intestine) associated with toxicity effect of papain papaya (Carica papaya L.). Seventy-eight adult BALB/c mice of both sexes were divided into 5 groups: 1 control group and 4 treatment groups that were given papain feeding block. Feed intake and mortalities have been monitored in previous study. At the end of the experimental period, tissues of mice were harvested for necropsy and histopathological examination. The abnormality of post mortem examination were hepatomegaly, gastro-intestinal bleeding. Dark discoloration was founded in liver and gaster. Histopathological changes founded in all treatment albino mice were necrosis in gaster, kidney, liver and intestine. Cloudy swelling occurred in liver and dilatation in kidney. Fatty degeneration occured in gaster, liver and intestine. In addition, the kidney and liver were congested. Feed intake of 16 to 32% papain natural rodenticide gave effect to the organs of studied mice, i.e gaster, kidney, liver and intestine.Reports on the rodenticide effect of papain papaya to control rats and mice is scarce. The aim of this study was to determine pathological changes in  albino mice internal organs (gaster, kidney, liver and intestine) associated with toxicity effect of papain papaya (Carica papaya L.). Seventy-eight adult BALB/c mice of both sexes were divided into 5 groups: 1 control group and 4 treatment groups that were given papain feeding block. Feed intake and mortalities have been monitored in previous study. At the end of the experimental period, tissues of mice were harvested for necropsy and histopathological examination. The abnormality of post mortem examination were hepatomegaly, gastro-intestinal bleeding. Dark discoloration was founded in liver and gaster. Histopathological changes founded in all treatment albino mice were necrosis in gaster, kidney, liver and intestine. Cloudy swelling occurred in liver and dilatation in kidney. Fatty degeneration occured in gaster, liver and intestine. In addition, the kidney and liver were congested. Feed intake of 16 to 32% papain natural rodenticide gave effect to the organs of studied mice, i.e gaster, kidney, liver and intestine.
Risk Factors of Covid-19 Transmission among Health Workers in Southeast Asia Prathiwi, Qonitah Fitri; Rejeki, Dwi Sarwani Sri; Wijayanti, Siwi Pratama Mars
Indonesian Journal of Global Health Research Vol 6 No 5 (2024): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v6i5.3453

Abstract

The transmission of Covid-19 to health workers is an important issue in the pandemic era. Health workers are the front line in handling Covid-19 so they are very vulnerable to being exposed to and even contracting Covid-19 disease. It is necessary to conduct an assessment of the factors that influence the transmission of Covid-19 to health workers, especially in the Southeast Asian Region. The aim of the systematic review is to examine the factors that influence the transmission of Covid-19 cases to health workers in Southeast Asia. The research journal database was retrieved by accessing PubMed and Google Scholar, and using the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) method using the keywords “risk factors” AND “transmission” AND “Covid-19” AND “health workers”. After going through a series of selections, 11 research journals of 241 journals found that were published in 2020-2023 and were considered relevant for study. Based on the results and discussion of the systematic review, it is known that the factors that influence the transmission of Covid-19 to health workers in Southeast Asia are: average age, type of profession, comorbid history, travel history, community contact at work, contact with Covid-19 patients, adherence to the use of PPE and implementing health protocols, levels of workload, levels of stress and immunization status of health workers.
Co-Authors Dwi Sarwani Sri Rejeki Eva Lestari Nova Pramestuti Prathiwi, Qonitah Fitri Sianturi, Corry Laura Junita