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Khederlou, Hamid
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Medicine & Pharmacology

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Dilated Cardiomyopathy in Behcet's Disease in a Young Male Patient Khederlou, Hamid; Taheri, Samin; Sadeghi, Alireza; Moghtader Mojdehi, Amirhossein
International Journal of Cardiovascular Practice Vol 2, No 4 (2017)
Publisher : International Journal of Cardiovascular Practice

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (197.514 KB) | DOI: 10.21859/ijcp-030102

Abstract

Behcet?s disease is a multisystemic, inflammatory and chronic disorder characterized by recurrent oral aphthous ulcers and genital ulcers, uveitis and other manifestations, including systemic organ involvement. Cardiac involvement in Behcet?s disease is rarely however, it plays an important role in prognosis and increases mortality. We hereby have reported a case of Behcet's disease with dilated cardiomyopathy. He was presented with constitutional symptoms and also oral and genital aphthous ulcers, pseudofolliculitis, tachycardia, arthritis, splenomegaly, ESR (erythrocyte sedimentation rate) and CRP (C-reactive protein) elevation and LV systolic dysfunction with LVEF=45% were found in evaluation. He was started on Azathioprine and Prednisolone.
LEFT VENTRICULAR HYPERTROPHY IN FABRY'S DISEASE IN AN OLD MALE PATIENT Firuzi, Mohadese; Khederlou, Hamid; Mohammadi, Narges
International Journal of Cardiovascular Practice Article in Press
Publisher : International Journal of Cardiovascular Practice

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (601.346 KB) | DOI: 10.29252/27629

Abstract

Fabry disease is an X-linked disorder due to deficiency of the lysosomal hydrolasea-galactosidase A and the resultant accumulation of glycosphingolipids throughout the body, such as in the heart. Cardiac manifestations in Fabry disease are due to glycosphingolipid deposition in the myocardium, valves, and conduction system. Fabry cardiomyopathy, characterized by progressive severe concentric left ventricular hypertrophy. We, as a result of this, have reported a case of Fabry disease with left ventricular hypertrophy. He was admitted with dyspnea and also dizziness, general weakness, and acroparesthesias. Physical examination showed Angiokeratoma on the skin. The electrocardiography revealed ST-segment depression in leads V3?V6, and changes related to left ventricular hypertrophy. Echocardiography showed concentric left ventricular hypertrophy.
Co-Authors Firuzi, Mohadese Moghtader Mojdehi, Amirhossein Mohammadi, Narges Sadeghi, Alireza Taheri, Samin