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Bozorgmehr, Rama
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Medicine & Pharmacology

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Pulmonary thromboemboli in smokers and nonsmokers; Risk factors and anatomic disturbution of emboli in CT angiographies Pishgahi, Mehdi; Zarei, Leila; Mohaghegh, Pegah; Bozorgmehr, Rama
International Journal of Cardiovascular Practice Vol 4, No 2 (2019)
Publisher : International Journal of Cardiovascular Practice

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (601.933 KB) | DOI: 10.29252/ijcp-25213

Abstract

Introduction: Recognition of risk factors in different high-risk groups such as smokers in comparison with non-high risk groups would help to develop good preventive strategies for pulmonary thromboemboli (PTE). The purpose of this study was to investigate and compare clinical findings and risk factors in smoker and nonsmoker patients with pulmonary thromboembolism and assessing anatomical variant in pulmonary computerized tomography angiographies.Methods: In this descriptive study 260 consecutive patients suspected to have PTE underwent pulmonary computerized tomography angiographies in a training hospital since 2015 to 2018. Patient with documented PTE were enrolled. Clinical finding and risk factors were determined and compared between them.Results: From 260 patients 172 subjects (66.15%) had PTE and enrolled in the study. Fifty-six (32%) were smoker and 116 (68%) non-smoker. The smoker group was younger and male gender was more predominant. Oxygen saturation and inspired oxygen partial pressure differed between smokers and non-smokers (P < 0.05). The predisposing factors of thromboembolism and anatomic distribution of emboli were the same in smokers and non-smokers.Conclusion: Regarding different factors responsible for PTE in smokers and non-smokers, clinical presentation and anatomic distribution of PTE are comparable.
PREVALENCE OF NON-THROMBOEMBOLIC INCIDENTAL FINDINGS ON COMPUTED TOMOGRAPHY-PULMONARY ANGIOGRAPHY FOR PULMONARY Bozorgmehr, Rama; Pishgahi, Mehdi; Mohaghegh, Pegah; Bayat, Marziye; Khodadadi, Parastou; Ghafori, Ahmadreza
International Journal of Cardiovascular Practice Article in Press
Publisher : International Journal of Cardiovascular Practice

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (650.271 KB) | DOI: 10.29252/26716

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Introduction: Computed Tomography-Pulmonary Angiography (CTPA) is a noninvasive imaging modality for direct diagnosis of pulmonary thromboembolism. The potential advantage of CTPA is possible alternative and incidental findings in cases that PTE is ruled out. This study was performed to determine the prevalence of incidental findings in CTPA in patients suspected to have PTE.Methods: This cross-sectional retrospective study was performed in patients with suspected PTE admitted to Shohada-e-Tajrish Hospital in 2014 and 2015 and underwent CTPA for final diagnosis. Incidental findings in CTPA and associated clinical symptoms were assessed.Results: According to CTPA performed in 188 patients, PTE was diagnosed in 61 cases (32.4%). Prevalence of incidental abnormal findings in the two groups with and without PTE were 93.7% and 90.9%, respectively. The most common incidental finding was pleural effusion (42%). There was no significant association between clinical symptoms and incidental findings in CTPA in patients with suspected pulmonary embolism (P > 0.05). The only significant finding was association between lung mass and tachypnea (P=0.007).Conclusion: In patients with primary clinical symptoms of suspected pulmonary embolism, in most cases there was a wide range of incidental findings and simultaneous pathologies in CTPA mimicking the primary symptoms of pulmonary embolism. However, in this study there was no significant association between clinical symptoms and incidental findings. Determination of definite indications of CTPA in patients with suspected pulmonary embolism is necessary.
Co-Authors Bayat, Marziye Ghafori, Ahmadreza Khodadadi, Parastou Mohaghegh, Pegah Pishgahi, Mehdi Zarei, Leila