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All Journal Amerta Nutrition Sanus Medical Journal
Sampurno, Edi
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Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Other

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Karakteristik Mutasi EGFR pada Pasien Kanker Paru Jenis Adenokarsinoma yang Diterapi dengan Tyrosien Kinase Inhibitor (TKI) di Rumah Sakit Paru Dr. H.A Rotinsulu Bandung Puspita, Desi; Dwi Astuti, Vitri; Rina; Sampurno, Edi
Sanus Medical Journal Vol. 4 No. 1 (2022)
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka (UHAMKA Press)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/sanus.v4i1.8431

Abstract

This descriptive study describes the proportion of Epidermal Growth Factor Receptor (EGFR) mutations in lung cancer Adenocarcinoma patients at Rumah Sakit Paru (RS Paru) Dr. H. A Rotinsulu Bandung in the range of 2018 to 2020. EGFR mutations were examined using RGQ thera screen technology Real"‘Time Polymerase Chain Reaction from FFPE or cytology smear. There are 44 data point mutations after examining the EGFR mutation. 59% cases were 40"‘60 years old group dan 52 % were female. It was found that in this group 86% patient with single mutation and 16% had doube mutations. EGFR mutations occurred in Exon 21 L858R in 13 cases (30 %), Exon 21 L861Q in 1 case (2%), Exon 19del in 24 cases (55%), double mutation Exon 19 and Exon 20 T790M type in 2 cases (4%), double mutation Exon 19del and Exon 21 in 4 cases (9%).
Pandangan Ahli Gizi Tentang Pelayanan Gizi Berbasis Gen Di Indonesia : Pandangan Ahli Gizi Tentang Pelayanan Gizi Berbasis Gen di Indonesia Putri, Sintia Aurilia; Aji, Arif Sabta; Sampurno, Edi; Aprilia, Veriani; Zulfa, Ifana Fitria; Alfiana, Rina; Hafizhah, Rafiqah Dwita; Farhan, Alfina Ulfah; Surendran, Shelini
Amerta Nutrition Vol. 7 No. 2SP (2023): AMERTA NUTRITION SUPPLEMENTARY EDITION Special 3rd Amerta Nutrition Conferenc
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/amnt.v7i2SP.2023.269-275

Abstract

Background: Cardiometabolic diseases are principal contributors to mortality, morbidity, and healthcare costs. Additionally, many Single Nucleotide Polymorphisms (SNPs) have been associated with cardiovascular health outcomes. Nutrition professionals' perspectives on genetic-based nutritional services play a pivotal role in treating and preventing non-communicable diseases (NCDs). Objectives: This study aims to explore Indonesian nutritionists' viewpoints on gene-based nutrition services. Methods: Employing a qualitative phenomenological approach, six Indonesian nutritionists from key provinces (DKI Jakarta, West Java, Central Java, East Java, and DI Yogyakarta) participated in in-depth interviews. Themes encompassed nutritionists' views on gene-based nutrition's role in NCD prevention, genetics science, and genetic testing understanding. Thematic analysis was performed using Nvivo v.12. Results: Results showed that nutritionists had a substantial understanding of genetics and gene-based nutrition services, despite concerns about test costs. They comprehended gene-based nutrition's role in NCD prevention and acknowledged its significance in preventing NCDs. Conclusions: Within this study, Nutritionists express the importance of gene-based nutrition services in NCD prevention. To enhance engagement, nutritionists are encouraged to communicate genetic testing's value to the community. This dissemination will help advance  NCD prevention efforts.
Co-Authors Alfiana, Rina Aprilia, Veriani Arif Sabta Aji Dwi Astuti, Vitri Farhan, Alfina Ulfah Hafizhah, Rafiqah Dwita Puspita, Desi Putri, Sintia Aurilia Rina Surendran, Shelini Zulfa, Ifana Fitria