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All Journal Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya CRJIM (Clinical and Research Journal in Internal Medicine)
Kartika, Juspeni
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Biochemistry, Genetics & Molecular Biology Education Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Other

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The Role of Systematic Reviews in Hematological Diseases Treatment Kartika, Juspeni; Legiran, Legiran
Clinical and Research Journal in Internal Medicine Vol. 5 No. 1 (2024): Volume 5 No 1, May 2024
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.crjim.2024.005.01.08

Abstract

Evidence-based medicine utilizes medical literature to guide clinical decisions, diagnose and treat patients. Practitioners use evidence-based guidelines to support or oppose a medical intervention. Therefore, systematic reviews of high-quality randomized controlled trials are the highest quality reviews, as these investigations are at the top of the hierarchy of evidence-based medicine. In continuing medical education, systematic reviews are used to inform medical interventions that should be used or avoided in order to protect patient safety and improve health services based on evidence5. In addition, systematic reviews produce empirical and focused answers. Regarding the explanation above, the author would like to explain further regarding the role of systematic reviews in therapeutic approaches in the field of hematology.
Stem Cell in Breast Cancer Theraphy Kartika, Juspeni; Legiran
Clinical and Research Journal in Internal Medicine Vol. 5 No. 2 (2024): Volume 5 No 2, November 2024
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.crjim.2024.005.02.12

Abstract

There is a lot of research to support that cancer stem cell attract normal stem cell. The tendency of tumor cells to attract stem cells then becomes the basis for the use of stem cells in breast cancer theraphy. When neural stem cell applied as a carrier, it will make the amount, timing, and location of viral oncolytic or drug release can be precisely controlled. Finally, this situation will increase the effectiveness of breast cancer therapy and reduce side effects. This is a brief review about potency of stem cell as breast cancer treatment. This article aim to increased our knowledge about the potency of stem cell as breast cancer treatment. The tendency of tumor cells to attract stem cells then becomes the basis for the use of stem cells as enzyme/prodrug theraphy, secreted agent, viral oncolytic carrier or nanoparticle (drug) carrier which tends to be more localized around the tumor. When neural stem cell applied as a carrier, it will make the location, amount and timing of drug release or viral oncolytic can be precisely controlled.
PROFILE OF INTESTINAL PROTOZOAN PARASITES IN FARMING COMMUNITIES IN GISTING SUBDISTRICT, TANGGAMUS DISTRICT, LAMPUNG PROVINCE Suwandi, Jhons Fatriyadi; Saftarina, Fitria; Kartika, Juspeni
Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Vol. 12 No. 2 (2025): Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Univers
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/jkk.v12i2.542

Abstract

Intestinal parasitic infections remain a health problem in communities. Surveys of intestinal protozoan infections in Lampung Province are limited. The transmission of intestinal protozoan infections is generally through the oro-faecal route, which is related to environmental and behavioral factors. Farmers are one of the communities that are potentially infected. Gisting Sub District is one of the agricultural centers in Lampung Province. Farmers' contact with the environment will increase the risk of intestinal protozoan infection. This study aims to determine the Species of intestinal parasites found in farming communities. The design of this study is a descriptive observational survey. Feces collected were examined for parasitological examination at the Parasitology Laboratory, Faculty of Medicine, University of Indonesia. The results showed, the prevalence is 9.33%, consisting of Blastocystis sp. protozoa (6.67%), Entamoeba histolytica/dispar protozoa (1.33%), and a mixture of Blastocystis sp. and Endolimax nana (1.33%) among the research subjects.
Co-Authors Fitria Saftarina Jhons Fatriyadi Suwandi Legiran Legiran