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Kepatuhan Penggunaan Obat pada Pasien Hipertensi di Puskesmas Saepudin, .; Padmasari, Siwi; Hidayanti, Puri; Ningsih, Endang S
Jurnal Farmasi Indonesia Vol 6, No 4 (2013)
Publisher : Jurnal Farmasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (443.338 KB) | DOI: 10.35617/jfi.v6i4.148

Abstract

In addition to antihypertensive regimen, medication adherence plays an important role in therapeutic management of hyperensive patients. This research is aimerd to measure adherence to antihypertensive therapy in hypertensive patients at primary health center, and to investigate patient's characteristic associated with such adherence. Hypertensive patients attending two primary health centers in Sleman Yogyakarta during January-March 2011 were recruited as respondents in this research. Adherence to natihypertensive therapy was measured using MMAS (Morisky Medication Adherence Scale) containing 8 questions, and a respondent with MMAS score � 6 was categorized as adherent one. Statistical analysis using Chi-square has been done to investigate respondent characteristic associated with adherence. Out of 215 recruited respondents, 62.3% were adherent to antihypertensive therapy. Respondent characteristic associated with adherence are educational background level, monthly income, presence of other chronic disease, and antihypertensive regimen.Keywords : hypertension, medication sdherence, MMAS, primary health center
KUALITAS PERESEPAN OBAT GOLONGAN ANTIINFLAMASI NONSTEROID DI SALAH SATU RUMAH SAKIT SWASTA DI YOGYAKARTA Saepudin, .; Wiranti, Wulan
Jurnal Farmasi Indonesia Vol 4, No 1 (2008)
Publisher : Jurnal Farmasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35617/jfi.v4i1.9

Abstract

Non-steroidal anti-inflammatory drugs (NSAIDs) are used widely for treatment a variety of diseases. This research was aimed at knowing quality of NSAID prescribing for hospitalized patients at a private hospital in Yogyakarta. Data of NSAIDs utilization during 1 July 2006 â?? 31 December 2006 were collected from hospital pharmacy division and quantity of NSAIDs utilization were measured using ATC/DDD and DU90% methodology. Quantity of NSAIDs utilization was expressed as number of DDD/100 bed days. Results from this research showed there were 14 items of NSAIDs were prescribed with 37 brand names. There were 5 items of NSAIDs included in DU90% segment : Ketorolac (38,63%), ketoprofen (18,82%), mefenamic acid (16,59%), Diclofenac (15,36%), and meloxicam (5,23%). Based on relative risk gastrointestinal toxicity of NSAIDs, the prescription of NSAID at hospital where this research was conducted is not good because more than 50% NSAIDs were prescribed have a high risk of gastrotoxic effect such us ketorolac and ketprofen. ABSTRAK Penelitian ini dilakukan untuk mengetahui kualitas peresepan obat-obat golongan AINS berdasarkan tingkat keamanan relatif terhadap saluran pencernaan. Penelitian dilakukan dengan menggunakan sampel data peresepan obat selama 6 bulan, yaitu pada periode 1 Juli 2006 â?? 31 Desember 2006. Data penggunaan obat golongan AINS dikumpulkan dari catatan penggunaan obat di instalasi farmasi dan data yang dikumpulkan meliputi jenis obat, bentuk sediaan, kekuatan, serta jumlah penggunaan. Pengukuran kuantitas penggunaan obat dilakukan dengan menggunakan satuan unit DDD (Defined Daily Dose) yang dinyatakan dengan DDD/100 hari rawat, dan kualitas peresepan AINS dianalisis berdasarkan kriteria Drug Utilization 90% (DU90%). Dari penelitian yang dilakukan diketahui terdapat 14 jenis obat golongan AINS yang digunakan di rumah sakit tempat penelitian dilakukan, dengan 37 merek dagang, dan rata-rata penggunaan obat AINS setiap bulan adalah sebesar 7,92 DDD/100 hari rawat. Obat-obat AINS yang kuantitas penggunaannya berada pada segmen DU90% meliputi ketorolak, ketoprofen, asam mefenamat, diklofenak, dan meloksikam dengan persentase berturut-turut 38,63%; 18,82%; 16,59%; 15,36%; dan 5,23%. Berdasarkan tingkat keamanan relatif obat golongan AINS terhadap saluran pencernaan, kualitas peresepan obat golongan AINS di rumah sakit tersebut masih kurang baik karena lebih banyak mengunakan obat dengan risiko tinggi terhadap gangguan saluran pencernaan, seperti ketoprofen dan ketorolak dengan penggunaan lebih dari 50%.