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Simbolon, Roslan
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Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Health Professions Medicine & Pharmacology

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Aktivitas Ekstrak Daun Binahong(Anredera cordifolia (Ten.) Steenis) sebagai Antihiperurisemia dan Antioksidan pada Tikus Hiperurisemia Laksmitawati, Dian Ratih; Simbolon, Roslan
Jurnal Farmasi Indonesia Vol 9, No 1 (2017)
Publisher : Jurnal Farmasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (7559.601 KB) | DOI: 10.35617/jfi.v9i1.556

Abstract

ABSTRACT : The Binahong plant (Anredera cordifolia (Ten.) Steenis) has been used to treat several types of diseases. To find another possible biological activities, we investigated binahong leaves antihyperuricemic and antioxidant activity through in vitro assay of xanthine oxidase inhibiting activity of binahong ethanol extract and through in vivo assay by measuring uric acid and malondialdehyde (MDA) levels in plasma of hyperuricemic rat treated with binahong ethanol extract. Rat was induced into hyperuricemiccondition using chicken concentrate which is administered orally for 7 days and potassium oxonic through intraperitoneal routeon the last day. In treatment groups, rat were administered with extract at doses 200, 400 and 800 mg/kg BW respectively along the induction periods, while theother group were given allopurinol. On 7thday, the levels of plasma uric acid andMDA were measured by enzymatic methods and tiobarbituric acid reactive substances (TBARS) methodconsecutively. In vitro study shows that at 100 ppm,binahong leavesethanolic extract inhibit xanthine oxidase activity by24.33%, while in vivo study showedthe extract hadantihyperuricemic activity by decreasinguric acid levels at dose 800 mg / kgBB about 60,88% compared to hyperuricemia control group. Plasma MDA levels showed that hyperuricemia induction for 7 days was not enough to show significant increase of MDA levels.As conclusion, the ethanolic extract of binahong leaves could lower uric acid levels but in this study  itâ??s activity as antioxidant could not be proven through MDA measurements.
Pengaruh Kualitas Produk dan Brand Image Barbara Walden Hair Spray Terhadap Loyalitas Pelanggan dengan Kepuasan Konsumen Sebagai Variabel Intervening Simbolon, Roslan; Yantih, Novi; Widyastuti, Sri
JURNAL ADMINISTRASI & MANAJEMEN Vol 15, No 4 (2025): Jurnal Administrasi dan Manajemen
Publisher : Universitas Respati Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52643/jam.v15i4.7722

Abstract

Abstrak: Penelitian ini bertujuan untuk menganalisis pengaruh kualitas produk dan brand image terhadap loyalitas pelanggan dengan kepuasan konsumen sebagai variabel intervening pada pengguna Barbara Walden Hair Spray. Penelitian ini menggunakan metode kuantitatif dengan pendekatan deskriptif-verifikatif. Data primer dikumpulkan melalui kuesioner yang disebarkan kepada 100 responden dan dianalisis menggunakan metode Structural Equation Modeling (SEM) dengan perangkat lunak SmartPLS versi 3.2.9. Hasil penelitian menunjukkan bahwa brand image memiliki pengaruh positif dan signifikan terhadap kepuasan konsumen dan loyalitas pelanggan, baik secara langsung maupun tidak langsung melalui kepuasan konsumen sebagai variabel perantara. Sebaliknya, kualitas produk tidak berpengaruh signifikan terhadap kepuasan konsumen maupun loyalitas pelanggan. Temuan ini menegaskan bahwa brand image Barbara Walden hair spray memiliki peran dominan dalam membentuk kepuasan dan loyalitas pelanggan sementara kualitas produk tetap perlu dipertahankan agar konsistensi persepsi positif terhadap merek tidak menurun. Penelitian ini memberikan implikasi praktis bagi pelaku usaha untuk fokus pada strategi penguatan brand image melalui inovasi komunikasi dan pengalaman konsumen dan sekaligus memastikan standar kualitas produk tetap terjaga sebagai upaya mempertahankan dan meningkatkan loyalitas pelanggan. Kata Kunci: Kualitas Produk, Brand Image, Kepuasan Konsumen, Loyalitas Pelanggan.
Co-Authors Dian Ratih Laksmitawati Novi Yantih Sri Widyastuti