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All Journal Jurnal Kesehatan JPP Jurnal Kesehatan Poltekkes Palembang
Anzani, Bella Pratiwi
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Health Professions Medicine & Pharmacology Nursing Public Health

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LITERATURE REVIEW: PERBANDINGAN EFEKTIVITAS PLATELET RICH PLASMA (PRP) DENGAN ASAM HIALURONAT (HA) SEBAGAI TERAPI OSTEOARTHRITIS Anzani, Bella Pratiwi
Jurnal Kesehatan Vol 11, No 1 (2020): Jurnal Kesehatan
Publisher : Politeknik Kesehatan Tanjung Karang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (440.913 KB) | DOI: 10.26630/jk.v11i1.1608

Abstract

The prevalence of osteoarthritis is increasing with age. In osteoarthritis, there is a change in the joint process that fails to repair damaged cartilages and manifestations such as joint narrowing, osteophytosis, subcondral sclerosis, and abnormal bone shape. Pharmacological therapies such as analgesics, corticosteroids, glucosamine, chondroitin sulfate, and non-steroidal anti-inflammatory drugs are used together with viscosupplementation to help and improve the development of arthritis. Intra-articular injection therapy is also used as a good choice for osteoarthritis therapy. Hyaluronic acid (HA) and platelet-rich plasma (PRP) are the two choices of intraarticular therapy that can be used. Hyaluronic acid can reshape cartilage through aggregation with proteoglycans and can improve synovial fluid present in the joints, but therapy with hyaluronic acid has a long-lasting, expensive, and proven effect. Platelet-rich plasma (PRP) is a new therapy. PRP is obtained from blood centrifugation several times. PRP is very easy to get, cheap and non-invasive. PRP contains various growth factors that can regenerate damaged cartilages. PRP can be applied and has the same benefits as HA, but until now there has been no consensus that which is a better outcome between the two therapies. From various literature it is known that PRP is more effective than hyaluronic acid as osteoarthritis therapy.
HASIL PEMERIKSAAN DARAH RUTIN TERHADAP MANIFESTASI PERDARAHAN PADA ANAK DENGAN DIAGNOSIS INFEKSI DENGUE DI RS DR. A. DADI TJOKRODIPO Anzani, Bella Pratiwi
JPP JURNAL KESEHATAN POLTEKKES PALEMBANG Vol 14 No 1 (2019): JPP (Jurnal Kesehatan Poltekkes Palembang)
Publisher : Poltekkes Kemenkes Palembang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36086/jpp.v14i1.402

Abstract

Latar Belakang: Manifestasi klinis pada infeksi dengue yang timbul pada dewasa dan anak berbeda. Manifestasi yang sering muncul pada dewasa berupa myalgia, nyeri retro orbital, mual dan atralgia, sedangkan pada anak berupa myalgia, sakit kepala dan manifestasi perdarahan. Tujuan dari penelitian ini adalah mengetahui hubungan hasil pemeriksaan darah rutin terhadap manifestasi perdarahan pada anak dengan diagnosis infeksi dengue. Metode: Penelitian ini menggunakan analitik observasional dengan pendekatan cross sectional.Penelitian dilakukan di IGD RS Dr. A. Dadi Tjokrodipo pada bulan Oktober-Desember 2017. Jumlah sampel penelitian 24 orang dengan menggunakan total sampling. Pemeriksaan darah rutin dilakukan menggunakan hematology analyzer. Manifestasi perdarahan didapatkan dari anamnesis dan pemeriksaan fisik pasien. Hasil: Hasil yang didapatkan menggunakan uji fisher’s exact mengenai hubungan trombosit terhadap manifestasi perdarahan didapatkan p value 0,015. Hubungan leukosit terhadap manifestasi perdarahan didapatkan p value 0,423. Hubungan hematokrit terhadap manifestasi perdarahan didapatkan p value 1,00. Hubungan hemoglobin terhadap manifestasi perdarahan didapatkan p value 1,00. Kesimpulan: Terdapat hubungan yang bermakna antara jumlah trombosit terhadap manifestasi perdarahan, namun tidak terdapat hubungan bermakna antara leukosit, hematokrit dan hemoglobin terhadap manifestasi perdarahan pada pasien anak dengan infeksi dengue.
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