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All Journal Journal of Stem Cell Research and Tissue Engineering Journal Medical Informatics Technology
abirama, atria
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Computer Science & IT Dentistry Engineering Health Professions Immunology & microbiology Medicine & Pharmacology Public Health Veterinary

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Fragility Fracture of Proximal Tibia in A Wheelchair-Bound 54-Year-Old Female Patient Davidia, Zaky; Abirama, Atria
Journal Medical Informatics Technology Volume 2 No. 3, September 2024
Publisher : SAFE-Network

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37034/medinftech.v2i3.61

Abstract

Sedentary behavior is one of the risk factors of fracture, in which mild activity was found to be inversely associated with hip, vertebral, and total fracture. Other study also found non-linear association of fracture risk with lower and higher physical activity was associated with higher risk of any fracture compared to a mean physical activity. In this study, we reported a 54-year-old wheelchair bound female with fracture on the proximal tibia cause by low-energy trauma. This research underscores the importance of early identification of fracture risk factors, especially in vulnerable populations such as older adults who are wheelchair-bound. Early interventions that include lifestyle changes, increased physical activity, and nutritional management are essential to prevent further fractures and improve bone health. Identifying the risk of fractures on elderly patient may be beneficial for prevention of fractures especially in wheelchair-bound elderly individual.
INTRATUNNEL THE EFFECT OF ADMINISTRATION OF BONE MARROW MESENCHYMAL STEM CELLS (BM-MSCs) AND VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF) TENDON-BONE TO INTERFACE HISTOLOGICAL GRAFT ANTERIOR CRUCIATE LIGAMENT APPEARANCE AFTER RECONSTRUCTION IN RABBITS abirama, atria
Journal of Stem Cell Research and Tissue Engineering Vol. 2 No. 1 (2018): JOURNAL OF STEM CELL RESEARCH AND TISSUE ENGINEERING
Publisher : Stem Cell Research and Development Center, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (559.51 KB) | DOI: 10.20473/jscrte.v2i1.9258

Abstract

The success of the Anterior Cruciate Ligament (ACL) reconstruction using a tendon graft is determined by integration in the bone tendon-graft interface on the bone tunnel. The use of stem cells and growth factors proved to accelerate the healing of the bone tendon-graft interface. The aim of this study was to inveestigate the difference of histology picture in the tendon-bone tunnel model after ACL reconstruction with intratunnel intravenous allogenic bone marrow mesenchymalstemcells (BM-MSCs) and intratunnel vascular endothelial growth factor (VEGF). This research used Post-Test Only Control Group design with 20 rabbits divided into treatment group and control group. Each group performed histologic image evaluation (thickness of collagen fiber or sharpey fiber) at week 3 and 6. Evaluation of histology overview at week 3 and week 6 showed a significantly thicker thickness of collagen fiber or sharpey fiber in treatment group compared with control group (p <0.05). Intravenous administration of BM-SCs and VEGF after ACL reconstruction can speed healing of the bone tunnel significantly from week 3 and 6. The study by Faridyan et al has concluded that intravenous BM-SCs + VEGF increased ultimate tension strength in the bone-tendon interface significantly. In this study, intravenous administration of BM-SCs and VEGF gave histologic images showing acceleration of bone tunnel healing.Keywords:Anterior cruciate ligament reconstruction, allogenic bone marrow mesenchymal stem cells, vascular endothelial growth factor, graft tunnel healing, and Sharpey fiber.
Co-Authors Davidia, Zaky