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All Journal GANESHA MEDICINA Jurnal Indonesia Sosial Sains
Suardamana, I Ketut
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Humanities Astronomy Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Earth & Planetary Sciences Economics, Econometrics & Finance Energy Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Library & Information Science Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Physics Public Health Social Sciences

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PENATALAKSANAAN DAN PENCEGAHAN REAKSI HIPERSENSITIVITAS AKUT AKIBAT MEDIA KONTRAS Andari Kluniari, Ni Made Nova; Suardamana, I Ketut
Ganesha Medicina Vol. 3 No. 1 (2023)
Publisher : Universitas Pendidikan Ganesha

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23887/gm.v3i1.57851

Abstract

The used of iodinated contrast media have increased in recent years. It has been estimated that in the United States alone, 15 million procedures a year contrast media. Approximately 2-3 % patient do pyelogram and myelogram retrograde occurred anaphylactoid reaction. The reaction event during procedure using iodinated contrast media could be fatal. The activated mast cell was not mediated by IgE. Although the use of Low Osmolarity iodinated contrast media could lower the risk of allergic reaction, it was still possible to occur anaphylactoid reaction during the procedure. Here we reported allergic event after using contrast media during PCI procedure. The symptom was relieved with steroid and antihistamin therapy. In this report we focus to discuss the management of preventing allergic reaction and the therapy if the allergic reaction occur.
Descriptive Profile of Anaphylactic Reaction Patients Hospitalized at RSUP Prof. DR. I.G.N.G Ngoerah Period 2018-2023 Wijaya, Gede Bagus Rawida; Suardamana, I Ketut
Jurnal Indonesia Sosial Sains Vol. 5 No. 08 (2024): Jurnal Indonesia Sosial Sains
Publisher : CV. Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59141/jiss.v5i08.1215

Abstract

Introduction: Anaphylactic reaction is a severe, potentially life-threatening systemic hypersensitivity reaction caused by a specific allergen. This study aimed to evaluate the clinical profile of anaphylactic patients hospitalized in Prof. Dr. I.G.N.G. Ngoerah Hospital, Denpasar. Method: This was a cross-sectional descriptive study of anaphylactic patients hospitalized in our center from January 2018 to December 2023. Patients diagnosed with anaphylactic reactions were included in this study. All the data (demographic, clinical manifestations, potential trigger) were attained from medical records for descriptive analysis. Result: 292 patients were enrolled in this study; half were women (54,4%), and the median age was 38,50 years (interquartile range 24). The most common potential triggers were drugs (57%), followed by food (18,5%), blood products (14,1), insect bites, and other triggers (4,8%). Almost all patients experience skin and mucosal manifestations (99%). Anaphylactic shock occurs in only 22% of patients. Discussion: Previous studies have found similar results to our findings, and anaphylactic reaction caused by drugs was associated with a more severe reaction. The effect of estrogen hormones on more severe reactions has been reported in female mice, but human research is still limited. Conclusion: Further studies are needed to investigate the correlation between demographic characteristics or specific clinical manifestations with a severe reaction.
Co-Authors Andari Kluniari, Ni Made Nova Wijaya, Gede Bagus Rawida