Garuda - Garba Rujukan Digital

Erly Sitompul

Unknown Affiliation

Author-ID : 1363541

Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

Published : 3 Documents Claim Missing Document

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Articles

1

Antimicrobial Activity of Liquid Soap Containing Turmeric (Curcuma domestica val.) and Lemongrass (cymbopogon nardus l.) Leaf Juice Nazliniwaty; Erly Sitompul
Indonesian Journal of Pharmaceutical and Clinical Research Vol. 1 No. 1 (2018): Indonesian Journal of Pharmaceutical and Clinical Research
Publisher : Talenta Publisher

Abstract. The purpose of this study was to formulate an antimicrobial liquid soap containing 25% turmeric and lemongrass leaf juice. Lemongrass leaf juice and turmeric juice 25% were formulated into a liquid soap. Stability, pH and viscosity of the liquid soap were evaluated. For stability tests, the preparation was stored for 3 months at room temperaure. The pH test was measured by Hanna pH meter. The viscosity test,was measured by Brookfield viscometer.The antimicrobial activity of the liquid soap was measured by disc diffusion method using bacteria such as Staphylococcus epidermis, Eschericia coli, Microsporum gypseum and Candida albicans. Physical properties of the formulated liquid soap including pH, viscosity, and stability showed that it was stable for 3 months. The results of antimicrobial test of the liquid soap containing turmeric and lemongrass leaf juice showed that the inhibition diameter against Staphylococcus epidermis, Eschericia coli, Microsporum gypseum and Candida albicans were 22.89, 27.05, 24.30, and 33.05 mm, respectively, while the liquid soap without the juice were 20.76, 19.50, 20.50 and 21.46 mm, respectively. The soap was effective in inhibiting the growth of microbes. Combination of turmeric and lemongrass leaf juice increased the inhibitory zone diameter of the liquid soap for microbe. Keywords: Antimicrobial Agent, Lemongrass Leaf, Liquid Soap, Turmeric Leaf.

PEMBUATAN SABUN MADU DAN UJIAKTIVITAS TERHADAP Escherichia coli dan Staphylococcus aureus Nova Florentina Ambarwati; Erly Sitompul
Jurnal Farmanesia Vol 1 No 1 (2014): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (116.007 KB)

Madu adalah cairan manis yang berasal dari nectar tanaman yang diproses oleh lebah menjadi madu dan tersimpan dalam sel-sel sarang lebah. Sejak ribuan tahun yang lalu sampai sekarang ini, madu telah dikenal sebagai salah satu bahan makanan atau minuman alami yang mempunyai peranan penting dalam kehidupan. Dalam penelitian telah dilakukan pembuatan sabun madu. Kemudian diuji beberapa parameter sabun madu meliputi tinggi busa dan pH. Sabun madu tersebut di uji aktivitasnya terhadap bakteri dengan metode DifusiAgar, menggunakan cakram kertas dengan media pertumbuhan Mueller Hinton Agar (MHA) dan bakteri uji yang dipakai adalah Escherihcia coli dan Staphylococcus aureus. Hasil penelitian menunjukkan bahwa sabun madu memenuhi uji parameter sabun meliputi tinggi busa dan pH. Hasil uji aktivitas anti bakteri terhadap bakteri Escherihcia coli menunjukkan bahwa sabun madu dengan konsentrasi 5%, 10%, 20%, 30% dan 40% berturut- turut 5,93mm, 6,80mm, 7,10mm, 7,80mm, 8,40mm dengan blanko 9,96mm dan pada bakteri Staphylococcus aureus dengan konsentrasi 5%, 10%, 20%, 30% dan 40% berturut-turut 5,93mm, 6,60mm, 7,36mm, 7,96mm, 8,76mm dan blanko 9,76mm. Dari hasil penelitian dapat disimpulkan bahwa sabun madu mempunyai aktivitas antibakteri.

Antibacterial Activity of Ethyl Acetate Fraction of Passion Fruit Peel (Passiflora Edulis Sims) on Staphylococcus Aureus and Escherichia Coli Nugraha, Sony Eka; Suryadi Achmad; Erly Sitompul
Indonesian Journal of Pharmaceutical and Clinical Research Vol. 2 No. 1 (2019): Indonesian Journal of Pharmaceutical and Clinical Research
Publisher : Talenta Publisher

North Sumatera is one of the central areas of purple passion fruit production in Indonesia. Processing passion fruit into beverage products (passion fruit juice) produces peel has not been utilized. The use of passion fruit skin needs to be studied so that it can be useful as a raw material for antibacterial drug preparations. The aim of this study was to determine the phytochemical constituent screening and antibacterial activity of ethyl acetate fraction of purple passion fruit peel against Staphylococcus aureus and Escherichia coli. Simplicia and ethyl acetate fraction were determinated its phytochemical properties. The extraction process by percolation method using ethanol 96% and continue to fractionation process by liquid liquid extraction method using n-hexane and ethyl acetate. The antibacterial activity were tested against Staphylococcus aureus and Escherichia coli using agar diffusion method with paper discs. The result showed that the simplicia characteristic of passion fruit peel were water content of 8.64%, water soluble extract of 31.69%, ethanol soluble extract of 13.02%, ash total of 7.89%, and insoluble ash in acid of 0.816%. The phytochemical screening simplicia and ethyl acetate fraction showed the presence of flavonoids, glycosides, saponins and tannins. The antibacterial activity test showed that the ethyl acetate fraction has an effective inhibition at the concentration of 100 mg/ml against Staphylococcus aureus and Escherichia coli, it showed dose dependent manner. The ethyl acetate fraction of passion fruit peel (Passiflora edulis Sims) has an antibacterial activity on Staphylococcus aureus and Escherichia coli

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