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All Journal Indonesian Journal of Pharmaceutical and Clinical Research Jurnal Farmanesia
Erly Sitompul
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Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Antimicrobial Activity of Liquid Soap Containing Turmeric (Curcuma domestica val.) and Lemongrass (cymbopogon nardus l.) Leaf Juice Nazliniwaty; Erly Sitompul
Indonesian Journal of Pharmaceutical and Clinical Research Vol. 1 No. 1 (2018): Indonesian Journal of Pharmaceutical and Clinical Research
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (772.619 KB) | DOI: 10.32734/idjpcr.v1i1.204

Abstract

Abstract. The purpose of this study was to formulate an antimicrobial liquid soap containing 25% turmeric and lemongrass leaf juice. Lemongrass leaf juice and turmeric juice 25% were formulated into a liquid soap. Stability, pH and viscosity of the liquid soap were evaluated. For stability tests, the preparation was stored for 3 months at room temperaure. The pH test was measured by Hanna pH meter. The viscosity test,was measured by Brookfield viscometer.The antimicrobial activity of the liquid soap was measured by disc diffusion method using bacteria such as Staphylococcus epidermis, Eschericia coli, Microsporum gypseum and Candida albicans. Physical properties of the formulated liquid soap including pH, viscosity, and stability showed that it was stable for 3 months. The results of antimicrobial test of the liquid soap containing turmeric and lemongrass leaf juice showed that the inhibition diameter against Staphylococcus epidermis, Eschericia coli, Microsporum gypseum and Candida albicans were 22.89, 27.05, 24.30, and 33.05 mm, respectively, while the liquid soap without the juice were 20.76, 19.50, 20.50 and 21.46 mm, respectively. The soap was effective in inhibiting the growth of microbes. Combination of turmeric and lemongrass leaf juice increased the inhibitory zone diameter of the liquid soap for microbe. Keywords: Antimicrobial Agent, Lemongrass Leaf, Liquid Soap, Turmeric Leaf.
PEMBUATAN SABUN MADU DAN UJIAKTIVITAS TERHADAP Escherichia coli dan Staphylococcus aureus Nova Florentina Ambarwati; Erly Sitompul
Jurnal Farmanesia Vol 1 No 1 (2014): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (116.007 KB)

Abstract

Madu adalah cairan manis yang berasal dari nectar tanaman yang diproses oleh lebah menjadi madu dan tersimpan dalam sel-sel sarang lebah. Sejak ribuan tahun yang lalu sampai sekarang ini, madu telah dikenal sebagai salah satu bahan makanan atau minuman alami yang mempunyai peranan penting dalam kehidupan. Dalam penelitian telah dilakukan pembuatan sabun madu. Kemudian diuji beberapa parameter sabun madu meliputi tinggi busa dan pH. Sabun madu tersebut di uji aktivitasnya terhadap bakteri dengan metode DifusiAgar, menggunakan cakram kertas dengan media pertumbuhan Mueller Hinton Agar (MHA) dan bakteri uji yang dipakai adalah Escherihcia coli dan Staphylococcus aureus. Hasil penelitian menunjukkan bahwa sabun madu memenuhi uji parameter sabun meliputi tinggi busa dan pH. Hasil uji aktivitas anti bakteri terhadap bakteri Escherihcia coli menunjukkan bahwa sabun madu dengan konsentrasi 5%, 10%, 20%, 30% dan 40% berturut- turut 5,93mm, 6,80mm, 7,10mm, 7,80mm, 8,40mm dengan blanko 9,96mm dan pada bakteri Staphylococcus aureus dengan konsentrasi 5%, 10%, 20%, 30% dan 40% berturut-turut 5,93mm, 6,60mm, 7,36mm, 7,96mm, 8,76mm dan blanko 9,76mm. Dari hasil penelitian dapat disimpulkan bahwa sabun madu mempunyai aktivitas antibakteri.
Co-Authors Nazliniwaty Nova Florentina Ambarwati