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Mebendazole treatment in ascariasis re-infection of two-year-old boy in rural Ambon: a case report and literature review Thiono, Marischa Tita; Sutjonong, Tioky; Polanunu, Masayu Ramadhani; Husada, Dominicus
Indonesian Journal of Tropical and Infectious Disease Vol. 12 No. 3 (2024)
Publisher : Institute of Topical Disease Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ijtid.v12i3.57195

Abstract

Ascariasis is currently a health problem in developing countries, especially in rural areas. Successful control of ascariasis is highly dependent on therapeutic interventions, environmental, and individual hygiene practices. Ascariasis is generally asymptomatic but can cause severe problems if treated improperly. Treatment is available, but reinfection may occur. This case aims to emphasize the usage of mebendazole treatment in ascariasis reinfection. A two-year-old boy came to the hospital with mucus diarrhea and worms in the stool. Two months ago, he had the same symptoms and experienced improvement after taking pyrantel pamoate at the previous hospital. The patient was diagnosed with acute diarrhea with mild to moderate dehydration, re-infection ascariasis, and malnutrition. Mebendazole 100 mg was administered twice daily for 3 days. Treatment with mebendazole was repeated twice with an interval of one month after the previous therapy due to the presence of Ascaris lumbricoides eggs in fecal examination. Fecal examination in the third month revealed the absence of Ascaris lumbricoides egg. Mebendazole can be used as therapy for ascariasis reinfections. However, repeated therapy is required in some cases. By integrating repeated therapy with comprehensive control measures, including health education and improved sanitation infrastructure, sustainable progress in combating ascariasis can be achieved.
Profil Kematian Neonatal di Rumah Sakit Umum Daerah dr. M. Haulussy Regional Hospital, Indonesia: Hasil Penelitian Thiono, Marischa Tita; Polanunu, Masayu Ramadhani
Cermin Dunia Kedokteran Vol 52 No 2 (2025): Pediatri
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v52i2.1247

Abstract

Background: The infant mortality rate (IMR) is one of the indicators commonly used to determine overall public welfare. This study aims to look deeper into the profile of neonatal mortality in Maluku region, particularly at dr. M. Haulussy Regional Hospital. Methods: This study was conducted on the neonatal population in the neonatal intensive care unit (NICU) of dr. M.Haulussy Regional Hospital DR M Haulussy from January 1, 2022, to August 31, 2023. A total of 34 neonates met the inclusion criteria. Results: The main factors causing neonatal death were respiratory failure/asphyxia, LBW, and sepsis with the percentage of 25.6%, 24.4%, and 22.2% respectively. Conclusion: The most common factors of neonatal mortality in this sample population were respiratory failure/asphyxia, LBW/BBLR/BBLT, and sepsis.