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Danuri, Hasim Muhamad
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Health Professions

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In Vitro α-Glucosidase Inhibition and Antioxidant Activity of Mulberry (Morus Alba L.) Leaf Ethanolic Extract Danuri, Hasim Muhamad; Lestari, Widia Ayu; Sugiman, Uci; Faridah, Didah Nur
Jurnal Gizi dan Pangan Vol. 15 No. 1 (2020)
Publisher : The Food and Nutrition Society of Indonesia in collaboration with the Department of Community Nutrition, IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (361.03 KB) | DOI: 10.25182/jgp.2020.15.1.45-52

Abstract

This present work aimed to investigate the in vitro antioxidant activity and α-glucosidase inhibitory effect of mulberry leaf ethanolic extract. Antioxidant analysis was performed using Thiobarbituric Acid (TBA) assay at concentrations of 125, 200, 500, and 1,000 ppm. The results showed that the optimum incubation time was four days and the extracts could reduce the formation of MDA, i.e. 41.21%, 45.33%, 44.19%, and 36.00%, respectively. This suggests that concentration of 200 ppm was found as the best treatment. In addition, the result showed that ethanolic extract of mulberry leaf also showed inhibition against α-glucosidase with the IC50 of 309.82 µg/ml.
Co-Authors Lestari, Widia Ayu Sugiman, Uci