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All Journal MNJ (Malang Neurology Journal)
Bertolini, Gladson Ricardo Flor
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Neuroscience

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HISTOLOGICAL ANALYSIS OF WISTAR RATS SCIATIC NERVES SUBJECTED TO COMPRESSION AND TREATED WITH LOW LEVEL LASER THERAPY AND NEURAL MOBILIZATION Antunes, Juliana Sobral; Karvat, Jhenifer; Bernardino, Giovanni Ribeiro; Kakihata, Camila Mayumi Martin; Brancalhão, Rose Meire Costa; Ribeiro, Lucinéia de Fátima Chasko; Aragão, Fernando Amâncio; Bertolini, Gladson Ricardo Flor
Malang Neurology Journal Vol 5, No 2 (2019): July
Publisher : Malang Neurology Journal

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.mnj.2019.005.02.1

Abstract

Background: The physical therapy resources, as Low-Level Laser Therapy (LLLT) and neural mobilization are usually used with regenerative purpose and for the relief of symptoms for peripheral nerve injury. However, there is a lack of consensus on its effects as well as its association. Objective: Evaluate the influence of low-level laser therapy (LLLT) associated with neural mobilization (NM) on nerve regeneration of female Wistar rats subjected to sciatic compression. Methods: Twenty four Wistar rats were divided into: G1 (Placebo), G2 (NM), G3 (LLLT) and G4 (NM+LLLT), all animals were subject to compression of the right sciatic nerve. The treatment occurred on the 3rd, 5th, 7th, 10th, 12th and 14th postoperative day (PO). On the 17th PO the animals were euthanized. Histological and morphometric analysis of the right (compression) and the left (control) sciatic nerve were performed.Results: In the morphometric analysis no significant differences between groups, but differences among sides were found. Histological analysis revealed the presence of inflammatory infiltrate and disruption of nerve fibers in the right sciatic nerves.Conclusion: Both techniques used (LLLT and neural mobilization), isolated and associated, on the parameters proposed, were not effective to accelerate the process of nerve regeneration.
PHOTOBIOMODULATION ON MUSCLE STRENGTH AND FATIGUE IN MULTIPLE SCLEROSIS: SYSTEMATIC REVIEW Santos, Heber; Santos, Yasmim; Ribeiro, Bianca; Artioli, Dérrick; Buzanello, Márcia; Bertolini, Gladson Ricardo Flor
MNJ (Malang Neurology Journal) Vol. 10 No. 2 (2024): July
Publisher : PERDOSSI (Perhimpunan Dokter Spesialis Saraf Indonesia Cabang Malang) - Indonesian Neurological Association Branch of Malang cooperated with Neurology Residency Program, Faculty of Medicine Brawijaya University, Malang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.mnj.2024.010.02.11

Abstract

Background: Photobiomodulation plays an important role in modulating the inflammatory process, accelerating tissue repair, which can be beneficial in cases such as multiple sclerosis. Objective: To carry out a literature review about effectiveness of photobiomodulation on muscle strength and fatigue in multiple sclerosis. Methods: The databases included were PubMed, Embase, Cochrane, Web of Science, Scopus and LILACS (Latin American and Caribbean Health Sciences Literature). Also the gray literature: Google Scholar, LIVIVO (ZB MED Search Portal for Life Sciences), Open Grey and Library of Thesis and Dissertations CAPES (Coordenação de Aperfeiçoamento de Pessoal de Nível Superior). The risk of bias was assessed using the Cochrane tool, Rob 2, and the data was extracted and assessed by blinded reviewers. Results: Initially 7302 records were found, 7102 in the main databases and 200 in the gray literature.  After removing duplicates, 4217 studies were left for Phase 1 and 10 for Phase 2. Finally, 3 randomized clinical trials were included in this review. Conclusion: The studies included risk of bias in this review was predominantly low. PBM proved to be effective in improving muscle strength, but not fatigue. However, the number of human clinical trials is still too few for a more conclusive analysis.
Co-Authors Antunes, Juliana Sobral Aragão, Fernando Amâncio Artioli, Dérrick Bernardino, Giovanni Ribeiro Brancalhão, Rose Meire Costa Buzanello, Márcia Kakihata, Camila Mayumi Martin Karvat, Jhenifer Ribeiro, Bianca Ribeiro, Lucinéia de Fátima Chasko Santos, Heber Santos, Yasmim