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Evaluasi Penggunaan Klorokuin Atau Oseltamivir Terhadap Fungsi Ginjal Pasien COVID- 19 di RSUP Fatmawati Jakarta Tahun 2020 Juwita, Agnes
Jurnal Farmasi Klinik Best Practice Vol 2 No 1 (2023): Jurnal Farmasi Klinik Best Practice
Publisher : RSUP Fatmawati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58815/jfklin.v2i1.26

Abstract

Coronavirus Disease2019 (COVID-19) is a new type of coronavirus (SARSCoV-2) that resembles a case of pneumonia. This virus was first discovered in Wuhan, China. In the early period of COVID-19 in March 2020 there was a significant increase in active cases and death cases in Indonesia. There is no therapeutic treatment for COVID-19, so the use of chlorouin or oseltamivir and other drugs being tested has the potential for COVID-19. The use of drugs outside of indications can cause a decrease in function in several organs of the body, especially in the kidneys because many drugs are excreted through the kidneys. The purpose of the study was to evaluate the suitability of therapy using chloroquine or oseltamivir with the standard COVID-19 Treatment Protocol and its effect on kidney function of COVID-19 patients at the inpatient installation of Fatmawati Hospital for the period March-June 2020. The research method was descriptive observational through tracing the medical records of COVID-19 patients. with the study subjects being inpatients with confirmed COVID-19 aged 18 years who received chloroquine or oseltamivir and had normal kidney function at Fatmawati Hospital. The effect of the use of chloroquine or oseltamivir using a pre and post design which will be analyzed using a paired t test to see levels before and after use on kidney function parameters. (57 patients) standard. A total of 49.56% (56 patients) who were not suitable for therapy included a mismatch of dosage and duration of administration. The results of the Wilcoxon Test analysis on the concomitant use of chloroquine or oseltamivir serum urea and creatinine levels had Asymp values. Sig. (2-tailed) < 0.05 means that the use of chloroquine or oseltamivir affects the patient's kidney function.
PENYULUHAN PEMBUATAN MASKER ORGANIK BIJI COKLAT DI DUSUN LUBUK DALAM KECAMATAN TAMAN RAJO KABUPATEN MUARO JAMBI Febriyenti, 0la; Juwita, Agnes; Fadila, Aulia; Nursaya'bani, Dimas Saad; Sari, Gusti Nurmila; Yuniansyah, Lutfhi Suci; Andriani, Lili; Wati, Misna; Siregar, Ulica Elidawati
Martabe : Jurnal Pengabdian Kepada Masyarakat Vol 3, No 1 (2020): Martabe : Jurnal Pengabdian Kepada Masyarakat
Publisher : Universitas Muhammadiyah Tapanuli Selatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31604/jpm.v3i1.89-94

Abstract

Facial masks are skincare cosmetics that have many advantages, namely to prevent premature aging, maintain facial skin, detoxify the skin, cure acne, and cleanse pores. Chocolate (Theobroma cacao L.) is one of the leading commodities in Indonesia. The content of flavonoid compounds has potential as an antioxidant. Antioxidants that can prevent the entry of free radicals that can interfere with the activity of enzymes other than that can prevent wrinkling and age on the skin. This activity carried out, starting from the preparation of the cocoa organic mask extension material, the collections of content, the implementation of the natural mask extension in Dusun Lubuk Dalam. The results of this activity are mothers who can make organic masks from cocoa beans that are beneficial for facial skin health. Lubuk Dalam is one of the villages in Kemingking Dalam Taman Rajo, Muaro Jambi, which has significant natural resources and has excellent potential for use as preparation material. Natural resources, namely chocolate fruit often found in this region. Therefore, a program is needed to improve public understanding and knowledge about the use of herbs for skin health and cosmetic preparation through counseling activities. Besides, this program can increase the economic value of many plants that grow in Dusun Lubuk Dalam.