Prescription screening is one of the pharmaceutical services conducted by examining prescriptions according to administrative, pharmaceutical, and clinical requirements aimed at preventing medication errors. Administrative requirements ensure prescriptions legality while pharmaceutical requirements assure therapeutic success. The study aimto determine administrative and pharmaceutical completeness of prescriptions in Mranggen Pharmacy, Demak Regency.This study is a descriptive observational study using prospective data from prescriptions in Mranggen Pharmacy, Demak Regency, in February 2023. The study used forms to assess the completeness of administrative and pharmaceutical aspects. Complete administrative data includes prescription date, doctor's name, doctor's practice license number, doctor's signature, patient's name, gender, age, address, and weight. Complete pharmaceutical data includes drug name, dosage forms, drug strength, drug unit, drug quantity, and instructions for use. The data was analyzed quantitatively to determine the percentage of administrative completeness, pharmaceutical completeness, and both.This study involved 311 prescription sheets and 43 copies of prescriptions. The results indicate that 12.15% of prescriptions are complete administratively, 47.74% are complete pharmaceutically, and 9.32% are complete in both aspects. The name, quantity, and how or when to use the medication is 100% while the lowest completeness is the aspect of patient's weight, which is 14.2%