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All Journal Indonesian Journal of Cancer Chemoprevention Jurnal Informatika Teknologi dan Sains (Jinteks)
Setyawan, Feri
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Biochemistry, Genetics & Molecular Biology Computer Science & IT Control & Systems Engineering Medicine & Pharmacology

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APLIKASI PEMESANAN TIKET WISATA PANTAI MENGANTI BERBASIS MOBILE DENGAN INTERGRASI PEMBAYARAN DIGITAL Setyawan, Feri; Anggara, Afwan
Jurnal Informatika Teknologi dan Sains (Jinteks) Vol 6 No 4 (2024): EDISI 22
Publisher : Program Studi Informatika Universitas Teknologi Sumbawa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51401/jinteks.v6i4.4910

Abstract

Menganti Beach, known for its scenery, is one of the popular tourist destinations in Kebumen Regency. Currently, the process of ordering and paying for tourist tickets is still done manually, causing long queues at the counter and hampering operational efficiency. Therefore, a mobile-based tourist ticket ordering application with digital payment integration is expected to help managers in the ticket ordering and payment process to be more efficient in terms of time so as not to cause long queues. Otherwise, the long queues at the counter will continue, resulting in an unpleasant tourist experience and decreased interest in tourist visits, which ultimately has a negative impact on tourist income. To overcome this problem, the study designed and created a mobile-based application that includes ticket ordering, online payment, and ticket checking features. By using the Waterfall method, it is expected that the steps taken include problem analysis, data collection through surveys and interviews, system design, implementation, testing, and application maintenance to ensure all features are functioning properly. Interim results show that this application can help tourism managers improve the efficiency of the booking and payment process time, thereby providing a better experience for visitors.
HPLC Analysis with Evaluation of Antioxidant and Antisenescence Activities of Parijoto (Medinilla speciosa Reinw. ex Bl.) Methanolic Extract in Vero Cells Artanti, Anif Nur; Rohmani, Sholichah; Utami, Diyah Tri; Susanto, Nindita Clourisa Amaris; Zulpadly, M. Fiqri; Meitasari, Annisa Diyan; Darojati, Ulfa Afrinurfadhilah; Untari, Meta Kartika; Sasongko, Heru; Ermawati, Dian Eka; Setyawan, Feri
Indonesian Journal of Cancer Chemoprevention Vol 16, No 1 (2025)
Publisher : Indonesian Society for Cancer Chemoprevention

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14499/indonesianjcanchemoprev16iss1pp44-56

Abstract

Parijoto (Medinilla speciosa Reinw. ex Bl.) is a traditional medicinal plant rich in polyphenolic compounds that are associated with antioxidant and cytoprotective activities. The present study aims to investigate the phytochemical profile, antioxidant capacity, cytotoxicity, and anti-senescence effects of parijoto methanolic extract. The methanolic extract of parijoto (MEP) was subjected to qualitative thin-layer chromatography (TLC) for the detection of flavonoids, quantitative high-performance liquid chromatography (HPLC) for the determination of quercetin and naringin, and antioxidant activity assessment using the DPPH method. The mobile phase for quercetin analysis was water: acetonitrile (45:55), while for naringin, it was acetonitrile:water: formic acid (21:78.8:0.2). Cytotoxicity was evaluated in Vero cells using the MTT assay, while senescence in normal kidney cells was assessed by senescence-associated β-galactosidase (SA-β-gal) staining. Results showed that the extract contained quercetin (5.76±0.11 ppm). The extract exhibited strong antioxidant activity with an IC₅₀ value of 40.46 ppm. Cytotoxicity testing of MEP on Vero cells revealed low toxicity (529±0.77 μM) at physiologically relevant concentrations, supporting its safety for normal kidney cells. Moreover, in normal kidney cells, the extract conferred cytoprotective effects by reducing oxidative stress–induced damage and attenuating senescence-associated β-galactosidase. Collectively, these findings suggest that MEP exhibits potent antioxidant, cytoprotective, and anti-senescence activity in vitro, warranting further in vivo studies to validate its potential effects on kidney health and age-related cellular damage.
Co-Authors Anggara, Afwan Anif Nur Artanti, Anif Nur Darojati, Ulfa Afrinurfadhilah ERMAWATI, DIAN EKA Heru Sasongko Meitasari, Annisa Diyan Sholichah Rohmani, Sholichah Susanto, Nindita Clourisa Amaris untari, meta kartika Utami, Diyah Tri Zulpadly, M. Fiqri