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Journal : Indonesian Journal of Science and Technology

Monitoring heavy metal contamination levels and microbiological pollution in seawater of Agadir coastal zones Bazzi, Illyass; Mouaden, Khadija El; Chaouay, Aicha; Addi, Abdelaziz Ait; Hamdani, Mohamed; Issami, Souad El; Hilali, Mustapha; Hammouti, Belkheir; Abbiche, Khalid; Salghi, Rachid
Indonesian Journal of Science and Technology Vol 5, No 3 (2020): IJOST: VOLUME 5, ISSUE 3, 2020
Publisher : Universitas Pendidikan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.17509/ijost.v5i3.26208

Abstract

The objective of this study was to monitor the bacteriological contamination of the seawater of the marine fisheries of the coastal Agadir, Morocco. The study was focused on the diagnosis on the pollution in heavy metals, such as cadmium, lead, and mercury in five zones: the port of Imi Ouaddar fish boarding (zone Z1), the old port of Agadir (zones Z2 and Z3), the port of Agadir Marina (zone Z4), and the estuary of Oued Souss (zone Z5). The analyses were done by testing physicochemical parameters (such as pH, temperature, dissolved oxygen, salinity and conductivity) as well as microbiological and atomic adsorption analyses. The experimental results showed that the values of the physicochemical parameters were almost the same in all zones, while the microbial conditions were different, in which this is due to the existence of heavy metals. The more heavy metal concentrations affected the condition of microbes in the sea water, confirmed by the number of Escherichia coli. This study demonstrated the importance of controlling concentration of heavy metals for better sustainability of environment.
Triazolopyrimidine Derivatives: A Comprehensive Review of Their Synthesis, Reactivity, Biological Properties, and Molecular Docking Studies Mrayej, Hajar El; En-nabety, Ghizlan; Ettahiri, Walid; Jghaoui, Mohamed; Sabbahi, Rachid; Hammouti, Belkheir; Rais, Zakia; Taleb, Mustapha
Indonesian Journal of Science and Technology Vol 10, No 1 (2025): IJOST: April 2025
Publisher : Universitas Pendidikan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.17509/ijost.v10i1.80301

Abstract

Triazolopyrimidines are heterocyclic compounds with a unique structure and a wide range of applications in medicinal chemistry. The versatility of the triazolopyrimidine scaffold allows for the exploration and development of compounds with diverse pharmacological properties. This literature review encompasses the period from 2014 to 2022 and offers a comprehensive and inclusive overview of the synthesis, reactivity, and biological properties studies of triazolopyrimidines. The review summarizes the various synthetic methods used to prepare triazolopyrimidines and their reactions with different reagents. It also examines their pharmacological properties, such as anti-COVID-19 and anticancer effects, and their molecular docking analysis with relevant targets. The review aims to contribute to a better understanding of the potential applications of triazolopyrimidine in the field of medicinal chemistry. This literature review from 2014 to 2022 provides a comprehensive exploration of triazolopyrimidines, highlighting their diverse applications in medicinal chemistry. The review aims to offer a thorough understanding of triazolopyrimidines' versatility, serving as a valuable resource for advancing drug development in medicinal chemistry.