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All Journal Jurnal Ilmiah Cendekia Eksakta Jurnal Farmasi Sains dan Terapan (Journal of Pharmacy Science and Practice)
Devi, Sisca
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Agriculture, Biological Sciences & Forestry Chemical Engineering, Chemistry & Bioengineering Computer Science & IT Mechanical Engineering Medicine & Pharmacology

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PERBANDINGAN GUAR GUM DAN HIDROKSIPROPIL METIL SELULOSA SEBAGAI GELLING AGENT TERHADAP KARAKTERISTIK FISIK SEDIAAN MASKER PEEL OFF EKSTRAK DAUN SALAM (Syzygium polyanthum) Devi, Sisca; Widiyana, Widiyana
CENDEKIA EKSAKTA Vol. 7 No. 1 (2022)
Publisher : Universitas Wahid Hasyim

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31942/ce.v7i1.6548

Abstract

Radikal bebas bersifat reaktif dan tidak stabil sehingga dapat menyebabkan penuaan dini. Radikal bebas dapat diatasi dengan senyawa antioksidan. Daun salam (Syzyum polyanthum) mengandung senyawa flavonoid yang bermanfaat sebagai antioksidan. Sediaan kosmetik yang cocok untuk penghantaran efek antioksidan adalah masker peel off. Salah satu bahan dalam formulasi masker peel off adalah gelling agent. Penelitian ini bertujuan untuk mengetahui perbedaan karakteristik fisik gelling agent guar gum dan hidroksipropil metil selulosa pada sediaan masker peel off ekstrak daun salam. Penelitian ini merupakan penelitian eksperimental menggunakan 2 jenis gelling agent yang berbeda pada 2 formula yaitu semi sintetik (HPMC K100M) dan gom alam (guar gum). Formula masker peel off dievaluasi karakteristik fisik meliputi organoleptis, pH sediaan, homogenitas, daya lekat, daya sebar, waktu mengering, dan viskositas. Hasil pengujian dianalisis dengan membandingkan hasil karakteristik fisik masing-masing formula menggunakan uji t dan uji Mann Whitney dengan taraf kepercayaan 95%. Hasil uji karakteristik fisik masker peel off ekstrak daun salam menunjukkan terdapat perbedaan bermaknapada  uji daya lekat dan waktu mengering.Kata kunci: ekstrak daun salam (nama latin), guar gum, hidroksi metil selulosa, masker peel off
Perbedaan Kombinasi Konsentrasi Bahan Pengikat Pati Garut (Maranta Arundinaceae. L) Dan Pati Talas (Colocasia Esculanta L. Scoot) Terhadap Karakteristik Fisik Sediaan Tablet Hisap Ekstrak Jahe Merah (Zingiber Officinale Var. Rubrum) Devi, Sisca; Baiti, Hilma Nur
Jurnal Farmasi Sains dan Terapan (Journal of Pharmacy Science and Practice) Vol. 11 No. 2 (2024): October
Publisher : Faculty of Pharmacy, Widya Mandala Surabaya Catholic University, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33508/jfst.v11i2.5290

Abstract

Red ginger contains gingerol which is used as a throat lozenge. One of the dosage forms used in developing the use of red ginger is lozenges. Making lozenges requires additional ingredients in the form of a binder which can be obtained from starch. Arrowroot starch and taro starch contain amylose and amylopectin which have the ability to adhere. The combination of the use of arrowroot starch and taro starch binders has an impact on the characteristics of the lozenges produced. This research aims to determine the differences in the combination of using concentrations of binding agents, namely arrowroot starch and taro starch, on the physical characteristics of red ginger extract lozenges.This research is an experimental study with the independent variable being the combination of concentrations of arrowroot starch and taro starch (100:0); (50:50); (0:100). Testing of the physical characteristics of red ginger extract lozenges included organoleptic and tablet dimensions, weight uniformity, tablet hardness and friability and disintegration time. Analysis of normally distributed and homogeneous data using One-Way Anova at a confidence level of 95% followed by Post Hoc testing. The Kruskal-Wallis test is used for data that is not normally and homogeneously distributed followed by the Mann Whitney test.The test results showed that the combination of concentrations of arrowroot starch and taro starch binders had an effect on the physical characteristics, namely tablet hardness and brittleness and tablet disintegration time (p<0.05).
Co-Authors Baiti, Hilma Nur Widiyana, Widiyana