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Wirnawati, Wirnawati
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Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Economics, Econometrics & Finance Environmental Science Immunology & microbiology Medicine & Pharmacology Public Health Social Sciences

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Formulation and Physical Quality Testing of Solid Soap From a Combination of Citronella Oil with Patchouli Leaf Oil Againts Staphylococcus aureus Bacteria Pradana, Anugrah Riska; Hamzah, Hasyrul; Dewi, Sinta Ratna; Wirnawati, Wirnawati
Journal of Islamic Pharmacy Vol 9, No 1 (2024): J. Islamic Pharm.
Publisher : Universitas Islam Negeri Maulana Malik Ibrahim Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/jip.v9i1.26885

Abstract

Bacteria on the skin can cause infections ranging from mild to quite serious. Bacteria that are commonly found on human skin are the pathogenic bacteria Staphylococcus aureus. The choice for making antibacterial solid soap based on active ingredients from patchouli oil and citronella oil is that this oil has inhibitory power in the growth of bacteria on the skin, one of which is Staphylococcus aureus. The aim of this research is to determine how large the inhibition zone is produced by the antibacterial solid soap formulation and to determine the characteristics and physical quality tests of the solid soap preparation combining citronella oil with patchouli leaf oil so that it is safe to use. The method used is a pure experimental method. Data collection was carried out for 4 weeks according to the testing time and then analyzed using the Graphad application. The results of the research on the inhibition zone test used 2 concentrations, namely 50% and 100%, each formulation had different average results, namely at F2 50% the average was 21 mm with a very strong category, at F2 100% the average was 19.5 mm with the strong category, at F3 50% we get an average of 16 mm in the strong category and at F3 100% we get an average of 18.6 mm in the strong category. In the tests that have been carried out, it was concluded that citronella oil and patchouli leaf oil can be made into antiseptic solid soap and can inhibit the growth of Staphylococcus aureus bacteria. The results of testing physical quality characteristics for 4 weeks have met the standard requirements for solid soap.
Formulasi Sediaan Krim Anti Jerawat Ekstrak Etanol Daun Sungkai (Peronema Canescens Jack) dan Uji Aktivitas terhadap Bakteri Propionibacterium Acnes dan Staphylococcus Aureus Putri Novianti, Eka; Wirnawati, Wirnawati
Jurnal Global Ilmiah Vol. 1 No. 10 (2024): Jurnal Global Ilmiah
Publisher : International Journal Labs

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55324/jgi.v1i10.104

Abstract

Penelitian ini bertujuan untuk mengetahui apakah ekstrak etanol daun sungkai dapat digunakan sebagai krim anti jerawat serta menentukan krim yang disiapkan dapat menghambat pertumbuhan bakteri Propionibacterium acnes dan Staphylococcus aureus. Penelitian ini merupakan penelitian metode eksperimental dengan metode uji antibakteri difusi sumuran dengan variabel uji yaitu variasi krim ekstrak etanol 2%, 4%, dan 6%, kontrol positif krim jerawat benzolac, dan kontrol negatif krim tanpa ekstrak. Hasil ekstrak etanol daun sungkai dapat dijadikan sediaan krim yang baik serta didapatkan rata-rata pemeriksaan zona hambat krim ekstrak etanol 0 mm, 13 mm, dan 17,7 mm terhadap bakteri S. aureus dan 0 mm, 7,23 mm dan 13,23 mm terhadap bakteri P.acne. Kesimpulannya bahwa krim ekstrak etanol dapat menghambat pertumbuhan bakteri S. aureus dan P.acne terdapat perbedaan aktivitas antibakteri pada tiap konsentrasi krim ekstrak etanol daun sungkai terhadap S. aureus dan P.acne. Hasil penelitian ini diharapkan agar masyarakat menerima informasi baru tentang sediaan krim ekstrak etanol daun sungkai yang dapat menghambat pertumbuhan Propionibacterium acnes dan Staphylococcus aureus dan dapat menjadi salah satu bentuk sediaan yang digunakan untuk mengobati jerawat.
Co-Authors Hamzah, Hasyrul Pradana, Anugrah Riska Putri Novianti, Eka Sinta Ratna Dewi