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All Journal Damianus Journal of Medicine Paediatrica Indonesiana
Susanti, Yurika Elizabeth
Unknown Affiliation
Health Professions Medicine & Pharmacology Public Health

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Gestational age, birth weight, and blood culture microbial patterns in late-onset neonatal sepsis Ramadhika, Muhammad; Iskandar, Stephen Diah; Yapiy, Ivana; Susanti, Yurika Elizabeth; Wijaya, Marcella Amadea; Rohsiswatmo, Rinawati
Paediatrica Indonesiana Vol 64 No 1 (2024): January 2024
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi64.1.2024.51-8

Abstract

Background The three main causes of neonatal deaths in Indonesia according to the WHO are sepsis, prematurity, and asphyxia. A suboptimal hospital environment increases the risk of late-onset neonatal sepsis (LONS), which in turn can prolong hospital stays. Objective To assess for possible associations of bacterial patterns in neonates with LONS, prematurity, and/or low birth weight. Methods Medical record data of 1,706 hospitalized neonates who were treated for sepsis or other disease in the Neonatal Unit, Dr. Cipto Mangunkusumo Hospital (CMH), Jakarta in 2020 were analyzed retrospectively. A total of 262 neonates had proven LONS. We assessed for possible risk factors such as gestational age, birth weight, and cultured blood microbes. Results Out of a total of 1,706 neonates admitted to the neonatal unit, the incidence of proven LONS was 15.4%. LONS was more prevalent (58.4%) in preterm than in full-term (41.6%) neonates. The majority (67.6%) of subjects with proven LONS were neonates with low birth weight (LBW) (<2,500 grams), and the largest percentage of them (35.1%) was in the 1,500-2,500-gram group. Gram negative bacteria emerged as the predominant pathogens of LONS patients in our hospital; the most common were Klebsiella pneumonia, Acinetobacter spp., Escherichia coli, Enterobacter spp., and Pseudomonas aeruginosa. Conclusion The proportion of LONS among LBW and preterm neonates is significantly higher compared to normal birth weight and neonates. In our unit, LONS was mostly caused by Gram-negative bacteria. The antibiotic susceptibility of the various pathogens causing LONS in CMH should be tested and compared to the current empirical antibiotic guidelines used in CMH.
DERAJAT FUNGSI MOTORIK KASAR DENGAN EPILEPSI PADA ANAK DENGAN PALSI SEREBRAL Susanti, Yurika Elizabeth; Kristiono, Marcelina Pepita; Jap, Arvin Leonard Sumadi; Himawan, Gratianus Billy; Khairi, Muhammad Rifqi; Hidayah, Nurul
Bahasa Indonesia Vol 24 No 2 (2025): Damianus Journal of Medicine
Publisher : Atma Jaya Catholic University of Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25170/djm.v24i2.6041

Abstract

Introduction: Epilepsy is a common comorbidity of cerebral palsy (CP). Variations in gross motor function affect functional outcomes in CP children significantly. This study aims to analyze the association between gross motor function and epilepsy in children with CP. Methods: A cross-sectional study was performed at the Pediatric Inpatient Ward, Outpatient Clinic, and Medical Rehabilitation Installation at Ulin General Hospital in Banjarmasin from July to September 2024. The subjects of the study were children between the ages of 2 and 18 who had been diagnosed with CP. We evaluated gross motor function utilizing the Gross Motor Function Classification System (GMFCS), categorizing the results into two groups: mild-moderate (GMFCS I-III) and severe (GMFCS IV-V) motor dysfunction. Chi-Square test was used for statistical analysis. Results: The study involved a total of 42 subjects diagnosed with CP. Twenty-eight subjects (66.7%) had epilepsy as a comorbidity. Twenty-three subjects experienced generalized seizures (82.1%), and 18 subjects were quadriplegic (64.3%). There were 17 subjects (40.5%) with mild-moderate motor dysfunction and 25 subjects (59.5%) with severe motor dysfunction. Twenty subjects with epilepsy showed severe motor dysfunction (71.4%). A significant association was identified between severe gross motor function and epilepsy in children with CP (p=0.026). Conclusion: Epilepsy was found to be significantly associated with cerebral palsy in children with severe gross motor dysfunction.
Co-Authors Himawan, Gratianus Billy Iskandar, Stephen Diah Jap, Arvin Leonard Sumadi Khairi, Muhammad Rifqi Kristiono, Marcelina Pepita NURUL HIDAYAH Ramadhika, Muhammad Rinawati Rohsiswatmo Wijaya, Marcella Amadea Yapiy, Ivana