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All Journal Indonesian Journal of Case Reports
Kisworini, Priyanti
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Health Professions Medicine & Pharmacology Neuroscience Public Health

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Liver Involvement During Flare-ups in Pediatric SLE: Lupus Hepatitis vs. Other Causes Utama, Adelia Anggraini; Kisworini, Priyanti; Raihan, Raihan
Indonesian Journal of Case Reports Vol. 1 No. 1 (2023): August 2023
Publisher : Heca Sentra Analitika

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.60084/ijcr.v1i1.48

Abstract

Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by production of autoantibodies that can affect multiorgan of the body, including the liver. Liver dysfunction is not part of the SLE classification criteria and rarely found compared to other organs. In patient with SLE with liver involvement signed by abnormal liver enzyme should consider whether it is SLE-associated hepatitis, known as lupus hepatitis, or cause by other entities such as drug-induced hepatitis, or a primary liver disease such as viral hepatitis and autoimmune hepatitis condition that coexisting with SLE. We are reporting a 13-year-old boy that has been diagnosed with SLE who had flare since he discontinued his medication by himself. He presented with jaundice, alopecia, oral ulcers, pale and malaise. Laboratory examination showed anemia, thrombocytopenia, elevated transaminases and bilirubin level. It is important to differentiate the cause of deranged liver function test in patient with SLE, because other entities may present similar to lupus hepatitis, but they have a different management and prognosis.
Managing an Atypical Case of Pediatric Cutaneous Polyarteritis Nodosa: Clinical Perspectives Managing Rare Presentation of Cutaneous Polyarteritis Nodosa in Pediatric Patient: Insight from a Case Study Utama, Adelia Anggraini; Kisworini, Priyanti; Putri, Niarsari Anugrahing
Indonesian Journal of Case Reports Vol. 3 No. 1 (2025): June 2025
Publisher : Heca Sentra Analitika

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.60084/ijcr.v3i1.265

Abstract

Cutaneous polyarteritis nodosa is a rare form of necrotizing vasculitis affecting small and medium-sized arteries, characterized by localized inflammation and ischemia without systemic organ involvement. This case report highlights a 7-year-old girl who presented with severe cutaneous manifestations, including digital necrosis and livedo reticularis, accompanied by arthralgia and myalgia. Laboratory findings revealed elevated inflammatory markers and a high anti-streptolysin O titer, indicating a possible post-streptococcal etiology. Angiographic evidence confirmed arterial occlusion in the left hand. The patient was treated with high-dose intravenous methylprednisolone, anticoagulation, and long-term methotrexate, resulting in symptom resolution and sustained remission over one year. This case emphasized the importance of prompt recognition, diagnosis, and multidisciplinary management of cutaneous polyarteritis nodosa to prevent and improve outcomes.
Co-Authors Adelia Anggraini Utama Niarsari Anugrahing Putri Raihan Raihan, Raihan Utama, Adelia Anggraini