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All Journal Current Biochemistry Alotrop Jurnal Pendidikan dan Ilmu Kimia
Kristina Mulia
Pendidikan Kimia, Universitas Bengkulu
Biochemistry, Genetics & Molecular Biology Chemistry Education

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Total Phenolic, Anticancer and Antioxidant Activity of Ethanol Extract of Piper crocatum Vahl from Pamekasan and Karang Asem Kristina Mulia; Akhmad Endang Zainal Hasan; Suryani Suryani
Current Biochemistry Vol. 3 No. 2 (2016)
Publisher : IPB University

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Abstract

Cancer is a deadly disease that ranks the second after heart disease. One of the causes of cancer is free radicals causing oxidative stress in humans. Antioxidant is compound that can reduce oxidative stress. The antioxidant activity is closely connected with anticancer activity. It is known that in addition to being an analgesic, aphrodisiac of Java chili also has potential as anticancer. This study examined the potential anticancer and antioxidant from the ethanol extract of Java chili from Pamekasan and Karang Asem. The method used in this study began with the extraction of Java chili using ethanol 70 %, phytochemical testing, determination of total phenol anticancer testing using MTT method on MCF-7 breast cancer cell line and antioxidant testing using DPPH. This study uses Java chili extract derived from Pamekasan and Karang Asem. IC50 value of the cytotoxic activity originating from the area Karang Asem amounted to 63.283 ppm and Pamekasan of 83.662 ppm. IC50 value of antioxidants samples derived from Karang Asem area of 285.613 ppm and are derived from Pamekasan amounted to 288.037 ppm.
Integration of Islamic Values In Thermochemistry Teaching Materials For Grade XI SMA/MA Krisandini, Triana; Mulia, Kristina
ALOTROP Vol. 9 No. 2 (2025): Jurnal Penelitian Pendidikan dan Ilmu Kimia
Publisher : University of Bengkulu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33369/alo.v9i2.46689

Abstract

This study aims to produce chemistry teaching materials for Thermochemistry that contain Islamic values. The development of teaching materials was carried out using the Four Steps Teaching Material Development (4STMD) method. This study focuses on the Design and Development stages. The results of the teaching material development at the Design stage produce a teaching material design. The Development stage in developing teaching materials uses the Four Steps Teaching Material Development (4STMD) method, which consists of four stages: selection, structuring, characterization, and didactic reduction. The first stage begins with a selection process that produces 11 competency achievement indicators and 18 concept labels that must be developed. In the source selection step, 2 international textbooks and 1 high school textbook were used. The results obtained at the structuring stage are concept maps; macro structures and three levels of representation that are in accordance with the context of daily life and Islamic values. Characterization was carried out by 30 high school students and it was found that 4 texts were included in the difficult to understand category so that didactic reduction was carried out. The results of the didactic reduction stage were texts that were difficult for students to understand were given treatment with a type of didactic reduction back to the qualitative and neglect stages. The conclusion obtained from the results of this development research was the formation of chemistry teaching materials for Thermochemistry material that integrated Islamic values.
FORMULASI DAN UJI EFEKTIFITAS SPRAY NABATI BERBASIS EKSTRAK DAUN PANDAN (Pandanus amaryllifolius) SEBAGAI REPELLENT SEMUT Kristina Mulia; Putri Soleha; Sefti Dahnia; Wentri Susanti; Zabrina Wardah A.Z
ALOTROP Vol. 10 No. 1 (2026): Jurnal Penelitian Pendidikan dan Ilmu Kimia
Publisher : University of Bengkulu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33369/alo.v10i1.49765

Abstract

House ants are one of the most common residential pests that can disturb comfort and potentially act as disease vectors. Repeated use of synthetic pesticides may cause negative impacts on human health and the environment; therefore, safer natural repellent alternatives are needed. This study aimed to determine the potential of pandan leaf extract (Pandanus amaryllifolius) as a repellent against black ants (Camponotus pennsylvanicus) and to identify the most effective optimum concentration. The study employed a Randomized Posttest-Only Control Group Design consisting of seven treatment groups, namely a negative control, pandan leaf extract concentrations of 5%, 10%, 15%, 20%, and 25%, and a positive control. Each treatment used 10 ants with four replications, resulting in a total sample of 280 ants. The test was conducted by observing the number of ants crossing the filter paper toward the bait within 10 minutes. Data were analyzed using the Kruskal–Wallis and Mann–Whitney U tests. The results showed that pandan leaf extract has potential as a natural repellent against black ants. The highest repellency percentage was obtained at concentrations of 15%, 20%, and 25%, each reaching 100%, while the 5% concentration showed a repellency rate of 89%. Statistical analysis indicated that all treatment groups were significantly different from the negative control (ρ < 0.05). The 20% concentration was considered the most optimal because it demonstrated high effectiveness without causing ant mortality. Therefore, pandan leaf extract has the potential to be developed as a more environmentally friendly botanical repellent for controlling domestic ants.
Co-Authors Akhmad Endang Zainal Hasan Putri Soleha Sefti Dahnia Suryani Suryani Triana Krisandini Wentri Susanti Zabrina Wardah A.Z