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All Journal Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML) Jurnal Medicare
Kunti Dewi Saraswati
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Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Neuroscience Nursing Public Health

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Association of Asprosin Levels in Metabolic Syndrome Jayanti, Evy Tri; maria diah, pramudianti; Kunti Dewi Saraswati
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol. 32 No. 1 (2025)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v32i1.2422

Abstract

Metabolic syndrome (MS) is a condition characterized by disruptions in the body's metabolism. The risk factors for MS are impacted by age, gender, body mass index (BMI), and low-density lipoprotein (LDL) to high-density lipoprotein (HDL) cholesterol ratio. Asprosin is a hormone protein secreted by white adipose tissue that stimulates oxidative stress and proinflammation, affecting changes in body metabolism that trigger the development of MS. To assess the relationship between serum asprosin levels, age, gender, BMI, and LDL/HDL cholesterol ratio on the incidence of MS where asprosin can be used as a single marker for predicting MS. An observational study with a cross-sectional approach was conducted at Dr. Moewardi General Hospital (RSDM) in Surakarta from November to December 2023, involving 85 consecutively sampled subjects. The population was selected based on inclusion criteria. Asprosin examination was performed using the Rayto RT 2100 instrument with the enzyme-linked immunosorbent assay (ELISA) method. Statistical analysis involved the use of the Kolmogorov-Smirnov test, followed by bivariate and multivariate analysis. There was a significant difference (p <0.001) between the MS and non-MS groups in terms of age, LDL/HDL cholesterol ratio, and asprosin variable. The mean serum asprosin level in the MS group was 25.81 (3.11-122.02) ng/mL. The cutoff value of asprosin was found to be >11.35 with a sensitivity of 83.3% and specificity of 79.1%. There was an association between serum asprosin levels, age, and LDL/HDL cholesterol ratio with the occurrence of MS. Further research is needed with a prospective cohort study design before and after the onset of MS.
HUBUNGAN ANTARA KONSUMSI ES TEH MANIS DENGAN RISIKO ANEMIA PADA MAHASISWI DI UNIVERSITAS SETIA BUDI Stevanus Zulkarnaen Wijaya Wara; Lucia Sincu Gunawan; Kunti Dewi Saraswati
Jurnal Medicare Vol. 4 No. 4 (2025): OCTOBER 2025
Publisher : Rena Cipta Mandiri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62354/jurnalmedicare.v4i4.275

Abstract

Anemia remains a global health problem, particularly among women of reproductive age. Sweet iced tea, which is widely consumed by young women, contains tannins, sugar, and caffeine that can inhibit iron absorption. This study aimed to determine the relationship between sweet iced tea consumption and the risk of anemia among female students at Setia Budi University, Surakarta. This analytical observational study used a cross-sectional design with 68 respondents selected through purposive sampling. Data were collected using a Food Frequency Questionnaire (FFQ) and blood tests (hemoglobin and erythrocyte indices). Data were analyzed using Fisher’s Exact test. The results showed no significant relationship between sweet iced tea consumption and the risk of anemia (p=0.480). Although tannins can inhibit iron absorption, moderate consumption frequency and the habit of drinking tea after meals may reduce this effect. Balanced nutrition education and healthy drinking habits are still needed to prevent anemia among young women.
Co-Authors Gunawan, Lucia Sincu Jayanti, Evy Tri maria diah, pramudianti Stevanus Zulkarnaen Wijaya Wara