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All Journal Jurnal Keperawatan dan Fisioterapi (JKF) Jurnal Pengmas Kestra (JPK) PCJN Pharmaceutical and Clinical Journal of Nusantara
Sitepu, Debi Dinha Octora
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Health Professions Medicine & Pharmacology Neuroscience Nursing Public Health Other

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The Effect of Giving Ginger Aromatherapy on Nausea and Vomiting in Cancer Patients Post Chemotherapy at Grandmed Hospital Lubuk Pakam wati, Syatria; Simarmata, Pratiwi Christa; Sitepu, Debi Dinha Octora; Anggraini, Dini
JURNAL KEPERAWATAN DAN FISIOTERAPI (JKF) Vol. 7 No. 2 (2025): Jurnal Keperawatan dan Fisioterapi (JKF)
Publisher : Fakultas Keperawatan dan Fisioterapi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jkf.v7i2.2660

Abstract

Cancer is one of the diseases that is the main cause of death in many parts of the country. In treating this disease, it can be done through chemotherapy, which can destroy cancer cells. However, there are side effects that can be felt by patients, namely nausea and vomiting. These symptoms can interfere with the patient's quality of life so that they become less compliant in following the next therapy. To overcome this nausea and vomiting condition, a type of non-pharmacological therapy can be tried, such as giving ginger aromatherapy which is known to contain active compounds such as gingerol and shogaol which can relieve these symptoms. Quantitative research with a Quasy Experiment design with a One Group Pretest Posttest approach was chosen in this research. A sample of 23 people was determined using the purposive sampling method. Analysis was carried out on the characteristics of respondents and the effect of ginger aromatherapy on nausea and vomiting was tested using a paired sample t-test. The results showed a change in the mean value from 4.52 to 2.48 or a decrease of 2.04, with a t value of 4.97, and a p value of 0.000 which can be interpreted that ginger aromatherapy can reduce the level of nausea and vomiting in cancer patients after aromatherapy. Ginger aromatherapy has been proven to reduce nausea and vomiting levels, making it suitable for recommendation for cancer patients after chemotherapy, so it can provide comfort and improve the patient's quality of life.
Strengthening the Role of Family in the Management of Pressure Ulcers in Stroke Patients at Grandmed Hospital, Lubuk Pakam Wati, Syatria; Fauzan, Yovi; Ginting, Samuel; Simarmata, Pratiwi Christa; Sitepu, Debi Dinha Octora
JURNAL PENGMAS KESTRA (JPK) Vol. 5 No. 1 (2025): Jurnal Pengmas Kestra (JPK)
Publisher : Lembaga Penelitian dan Pengabdian Kepada Masyarakat (LP2M) Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/mmbqr630

Abstract

Stroke is a type of catastrophic illness characterized by high incidence and disability rates. It significantly impairs physical function and increases the risk of developing pressure ulcers. Pressure ulcers, or decubitus ulcers, occur due to prolonged pressure, friction, and moisture exposure, leading to skin tissue damage in areas of the body that bear weight during periods of immobility. Family support plays a crucial role in the rehabilitation of stroke patients, particularly in providing basic care, assisting with mobility, and preventing complications. This community engagement program (PkM) aimed to enhance family capacity in managing pressure ulcers through educational and practical interventions. Family involvement was facilitated through structured education and hands-on training to encourage active participation in supporting comprehensive patient recovery. The PkM activities were delivered using an educational and participatory approach to 25 participants, all of whom were family members of stroke patients currently hospitalized at Grandmed Hospital, Lubuk Pakam. The program implementation consisted of four stages: preparation, sample selection, execution, and evaluation. The results showed a significant improvement in participants’ knowledge, with an average increase of 32.6 points (59.1%) regarding the role of families in pressure ulcer care. Additionally, 92% of participants demonstrated competency in performing basic stroke care, and 96% expressed high satisfaction with the program. This PkM initiative effectively strengthened the role of families in managing pressure ulcers in stroke patients, thereby contributing to increased patient motivation and improved quality of life.
Antioxidant Activity of Pineapple Peel (Ananas comosus L.) Ethanol Extract Using CUPRAC and FRAP Methods Sitepu, Debi Dinha Octora; Maharani, Maharani
PCJN: Pharmaceutical and Clinical Journal of Nusantara Vol. 3 No. 02 (2025): PCJN: Pharmaceutical and Clinical Journal of Nusantara
Publisher : CV. Nusantara Scientific Medical

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58549/pcjn.v3i01.84

Abstract

Pineapple peel (Ananas comosus L.) is an agricultural by-product rich in phenolic compounds and flavonoids that may possess significant antioxidant properties. This study aimed to evaluate the antioxidant activity of 70% ethanol extract of pineapple peel using two complementary spectrophotometric methods: CUPRAC (Cupric Reducing Antioxidant Capacity) and FRAP (Ferric Reducing Antioxidant Power). The extraction was performed by maceration method yielding 14.77 ± 0.52% extract. Phytochemical screening confirmed the presence of flavonoids, tannins, phenolics, saponins, and terpenoids. Total phenolic content (TPC) was 68.42 ± 2.31 mg GAE/g and total flavonoid content (TFC) was 42.67 ± 1.84 mg QE/g. The CUPRAC method at 450 nm yielded a TEAC value of 312.5 ± 8.2 μmol TE/g, while the FRAP method at 593 nm yielded 198.4 ± 5.6 μmol Fe²⁺/g. EC50 values were 186.4 ± 6.3 μg/mL (CUPRAC) and 228.3 ± 7.4 μg/mL (FRAP), which were lower than vitamin C as positive control (89.7 ± 3.8 and 112.5 ± 4.2 μg/mL, respectively). Pearson correlation showed strong positive correlations between TPC/TFC and antioxidant activity (r = 0.9873 and 0.9645, p < 0.01). These results indicate that pineapple peel ethanol extract possesses moderate antioxidant activity attributable primarily to its phenolic and flavonoid content, warranting further studies on bioactivity-guided fractionation.
Co-Authors Dini Anggraini, Dini Fauzan, Yovi Ginting, Samuel Maharani Maharani, Maharani Pratiwi Christa Simarmata Syatriawati Syatriawati