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Comparison of The Effects of Fentanyl versus Ketamine on The Quality of Recovery Post General Anesthesia with QoR-40 Scoring in Laparotomy Surgery Syahputra, Imam; Irina, Rr Sinta; Lubis, Bastian
JAI (Jurnal Anestesiologi Indonesia) Vol 17, No 2 (2025): JAI (Jurnal Anestesiologi Indonesia)
Publisher : Perhimpunan Dokter Spesialis Anestesiologi dan Terapi Intensif

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jai.v0i0.68607

Abstract

Background: Evaluating recovery after general anesthesia is vital to assess the success of anesthesia procedures. The quality of recovery-40 (QoR-40) questionnaire comprehensively measures post-anesthesia recovery. Poor postoperative pain management can lead to complications and chronic pain. Researchers studied ketamine because of its potential to enhance standard analgesics, improve pain control, and promote better recovery outcomes.Methods: This double-blind, randomized controlled trial involved 42 patients undergoing laparotomy at Haji General Hospital, Medan. Participants were randomized into two groups: one receiving fentanyl at 0.7 µg/kg body weight (BW) and the other receiving ketamine at 0.2 mg/kg BW. Consecutive sampling was used for participant selection, including patients who met specific inclusion and exclusion criteria. The QoR-40 questionnaire, validated in Indonesian, was administered postoperatively to assess recovery across five dimensions: comfort, feelings, support, independence, and pain.Results: The results of the study showed that the total QoR-40 score for fentanyl use had an average of 172.4762 + 3.81601, while in the group using ketamine, the average score was 174.7619 + 3.37498, which had a significant difference between the fentanyl group and the ketamine group with p <0.05.Conclusion: Ketamine provides a superior quality of recovery compared to fentanyl, as evidenced by higher comfort and total QoR-40 scores. These findings support ketamine's use as an effective alternative in anesthetic protocols for laparotomy procedures, promoting better recovery and reducing dependence on opioids.
PEMBUATAN PESTISIDA NABATI DAUN PEPAYA DI DESA TANJUNG ALAM KECAMATAN SEI DADAP KABUPATEN ASAHAN Handayani, Turi; Fajri, Surya; Satria, Indra; Syahputra, Imam; Fadillah, Chika Intan
Jurnal Pemberdayaan Sosial dan Teknologi Masyarakat Vol 5, No 2 (2025): Desember 2025
Publisher : Smart Education

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54314/jpstm.v5i2.5384

Abstract

Abstract: Agriculture is a key sector supporting food security and the community's economy. One of the obstacles in agricultural activities is pest attacks, which are generally addressed with the use of chemical pesticides. However, excessive use of chemical pesticides can have negative impacts on human health and the environment. Therefore, alternative solutions are needed in the form of safer and more environmentally friendly botanical pesticides. This community service activity was carried out in Tanjung Alam Village through socialization of the manufacture of botanical pesticides from papaya leaves to students of SMP IT Adabiyah. The activity methods included counseling, a question and answer session, and hands-on practice in making botanical pesticides. The results of the activity showed that students understood the dangers of chemical pesticides and learned how to make botanical pesticides from simple ingredients easily found in the surrounding environment. This program is expected to increase environmental awareness, reduce dependence on chemical pesticides, and support the creation of sustainable agriculture in the community. Keywords: papaya leaves, socialization, botanical pesticides, socialization Abstrak: Pertanian merupakan sektor utama yang mendukung ketahanan pangan dan perekonomian masyarakat. Salah satu kendala dalam aktivitas pertanian adalah serangan hama yang umumnya diatasi dengan penggunaan pestisida kimia. Namun, pemakaian pestisida kimia secara berlebihan dapat menimbulkan dampak negatif bagi kesehatan manusia dan lingkungan. Oleh karena itu, diperlukan solusi alternatif berupa pestisida nabati yang lebih aman dan ramah lingkungan. Kegiatan pengabdian masyarakat ini dilaksanakan di Desa Tanjung Alam melalui sosialisasi pembuatan pestisida nabati berbahan dasar daun pepaya kepada siswa SMP IT Adabiyah. Metode kegiatan meliputi penyuluhan, sesi tanya jawab, serta praktik langsung pembuatan pestisida nabati. Hasil kegiatan menunjukkan bahwa siswa memahami bahaya pestisida kimia dan mengetahui cara pembuatan pestisida nabati dengan bahan sederhana yang mudah ditemukan di sekitar lingkungan. Program ini diharapkan dapat meningkatkan kesadaran lingkungan, mengurangi ketergantungan terhadap pestisida kimia, serta mendukung terciptanya pertanian berkelanjutan di masyarakat. Keywords: daun pepaya, sosialisasi, pestisida nabati, sosialisasi
Antidiabetic potential of andaliman: Histopathological and glycemic improvements in diabetic rats Simbolon, Boyke Marthin; Lina, Juliana; Saragih, Ayu Theresia; Bangun, Chrismas Gideon; Nasution, Muhammad Fauzi; Rosari, Anita; Dewani, Yunita; Syahputra, Imam; Silalahi, Todung Donald Aposan
Buletin Kedokteran & Kesehatan Prima Vol. 5 No. 1 (2026): March
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v5i1.7891

Abstract

Background: Diabetes mellitus (DM) is a metabolic disorder characterized by chronic hyperglycemia and pancreatic dysfunction, particularly involving the Islets of Langerhans. Andaliman (Zanthoxylum acanthopodium) is a plant rich in flavonoids and antioxidants, which are believed to have antidiabetic effects. This study aimed to evaluate the effectiveness of the ethanol extract of Andaliman fruit on pancreatic histopathology in alloxan-induced diabetic rats. Methods: This study employed a true experimental design with a pre-test and post-test control group structure. Twenty-four male Wistar rats were randomly assigned to six groups: a normal control, a positive control (metformin 9 mg/kg), a diabetic control (alloxan 90 mg/kg), and three treatment groups induced with alloxan followed by administration of Andaliman extract at doses of 150, 250, and 350 mg/kg body weight, respectively. Treatments were administered for 14 days, after which blood glucose analysis (pre- and post-treatment) and pancreatic histopathological assessments were performed. Results: Statistical analysis revealed a significant reduction in blood glucose levels following treatment (p = 0.001). Histopathological examination showed that Andaliman extract ameliorated alloxan-induced damage to the Islets of Langerhans. The 350 mg/kg body weight dose resulted in the most pronounced tissue regeneration compared to the other treatment groups. Conclusion: The ethanol extract of Andaliman fruit effectively improves pancreatic histopathology and lowers blood glucose levels in diabetic rats.