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All Journal Indian Journal of Forensic Medicine & Toxicology
Fatimah Kadhim Ibrahim AL- Mahdawi1, Zaid Nabeel Elia2, Hayder Abdulhafedh Kurji3
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Evaluation Inhibin B, FSH, and LH in Male with Thalassemia Fatimah Kadhim Ibrahim AL- Mahdawi1, Zaid Nabeel Elia2, Hayder Abdulhafedh Kurji3
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.3401

Abstract

Background : - Hypogonadism is the most frequently reported endocrine problem, affecting 70–80% of patients with thalassemia.Aim of study: -The current study is aimed to found correlation among inhibinB,FSH, LH and testosteronein male with thalassemia. Material and Subject: The study carried out 40 healthyvolunteermale, age range between (18-30) years,and enrolled 40 patients with thalassemia major age range between 18-30 years. The concentrations serum inhibin-B was estimated by two-side enzymelinked immunosorbent assays (ELISA), While FSH, and LH estimated by using Cobas e analyzers.Results: LH reduce significantly in thalassemia patients when compared with healthy individuals, while FSH and testosterone decrease significantly in thalassemia patients when compared with healthy. Inhibin B was reduced significantly in thalassemia patients when compared with healthy individuals.Conclusion:Infertility common in thalassemia patients, that correlation with decrease inhibin B.
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