Anfal Shakir Motib1 , Hani Hameed Wadi2 , Saja Khamees Sabae3
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Antibiotic Sensitivity of Streptococcus Pneumoniae that Isolated from Different Pneumococcal Infections Anfal Shakir Motib1 , Hani Hameed Wadi2 , Saja Khamees Sabae3
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 3 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i3.10673

Abstract

During the period from June of 2018 to February 2019 (150) isolates of Streptococcus pneumoniae were isolated from 600 patients with clinical symptoms of Lower respiratory tract infections (LRTI) (pneumonia), otitis media and meningitis obtained from Baqubah Hospitals. The results showed that not only S. pneumoniae causes pneumonia and it can causes diseases other than pneumonia such as otitis media and meningitis but with less frequency. S. pneumoniae showed different susceptibilities towards antibiotics used in this study. The total susceptibility was (65.8%) and the total resistance was (34.2%). The highest pneumococcal susceptibility was showed to the cell wall inhibitors (44.4%) followed by protein synthesis inhibitors (28%) and quinolones (17.3%), and the lowest susceptibility was to folate antagonists with 0%. The highest rates of susceptibility was to penicillin (100%), chloramphenicol (86%), vancomycin (80%) and moderate rates of susceptibility to levofloxacin (90) 60%, linezolid (42.7) %, cefotaxime (40%), ofloxacin (40%) whereas there was a relatively lower susceptibility rate towards other antibiotics such as ampicillin, imipenem, amoxicillin, trimethoprim/sulfamethoxazole. Therefore, it should be avoided in the treatment in addition to tazobactam, amikacin, gentamicin, which had lowest rates susceptibility against S. pneumoniae. As a result, it required more research to identify new antibiotic or vaccine to reduce the risk of pneumococcal infection.