Entesar A. Essa1 , Layla J. Mohammed2 , Jabbar H. Yenzeel3 , Sahar A. H. AL-Sharqi4
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Effect of Insecticide “Maxxthor” on Some Hematological and Oxidative Stress Parameters in Male Albino Rats Entesar A. Essa1 , Layla J. Mohammed2 , Jabbar H. Yenzeel3 , Sahar A. H. AL-Sharqi4
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.11776

Abstract

The present study was designed to investigate the effect of different concentrations of Maxxthor on somehematological and oxidative stress parameters in male albino rats.Twenty male rats with age of 6-8 weeks andweight of 200-250gm were equally divided into four groups as follow:G1 treated with normal saline as controlgroup,while G2,G3andG4groups were treated with(0.01,0.1,1)mg\kg body weight of Maxxthor respectivelyfor 40 days.The following hematological parameters were measured: red blood cell(RBC),hemoglobin(Hb),white blood cell(WBC), platelets(PLT),malondialdehyde(MDA),glutathione(GSH),catalase andvitamin E. The hematological parameters results revealed highly significant(p<0.01)decreasein RBC andH,while a highly significant(p<0.01)increase in WBC and PLT in all treated groups as compared with control.The oxidative stress parameters results revealed highly significant(p<0.01)increase in MDA level,whilehighly significant(p<0.01)decrease in GSH,catalase and vitamin E level were noticed in all treated groupsas compared with control .