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All Journal Indian Journal of Forensic Medicine & Toxicology
Salam Abbas1 , Noor Harith AL-Hamid
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Public Health

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Expression Studies of the Cancer Drug and Its Effect on Angiogenesis-Promoting Genes in Cancer Cell Lines Salam Abbas1 , Noor Harith AL-Hamid
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.11806

Abstract

Objective: Being a member of RNA binding proteins, Human Antigen R (HuR) is considered as an acutefactor to mediate the proangiogenic factors causing the angiogenesis amongst tumor cells. All through theanoxic conditions and inflammation, the cytokine IL-1 activated the HuR which further downregulated orupregulated the hypoxia inducible factors (HIF1?). Current study was conducted to observe the correlativeimpact of Decetexal (Taxotere) cancer drug on HIF? and HuR expression levels while utilizing the cell lineHeLa.
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