<![CDATA[Recurrent aphthous stomatitis is a disorder distinguished by ulcers restricted to the oral mucosa. Because ofthe histological similarities between peptic ulcers and recurrent aphthous stomatitis and the identified roleof Helicobacter pylori in peptic ulcer, the possibility of bacterial involvement in the progression of aphthaehas been suggested. Helicobacter pylori are one of the most common, well-known pathogenic agents in thedevelopment of peptic ulcers. Some investigators have shown a relationship between Helicobacter pyloriand recurrent aphthous stomatitis. However, this relationship is controversial. The aims and objectives ofthis study were 1- Clinical evaluation of patients with recurrent aphthous stomatitis.2- Determination of theassociation between Helicobacter pylori and recurrent aphthous stomatitis using the urea breath test.Eighty-five subjects were participated in this study; they are divided into two groups. Fifty patients withrecurrent aphthous stomatitis, which at least occur four, or more times per year, thirty-five healthy subjectsof the same age group as controls.The results showed that ,the mean age of patients with recurrent aphthous stomatitis lie around 3rd decadeand the percentage of female with recurrent aphthous stomatitis was higher than male,the clinical findingsshowed that the number of patients with minor recurrent aphthous stomatitis was higher than patients withmajor and Herptiform recurrent aphthous stomatitis , No difference between the number of patients who hadsingle recurrent aphthous stomatitis and number of patients who had multiple recurrent aphthous stomatitiswas found . According to the site of ulcers, the result founded that the number of patients who had RAS onthe non-keratinized mucosa was higher than patients who had RAS on the keratinized mucosa and those whohad recurrent aphthous stomatitis on keratinized and non-keratinized oral mucosa.Regarding the laboratory findings, the percentage of patients with recurrent aphthous stomatitis who ureabreath test positive was higher than percentage of control group,also the mean value (Delta Over Base) ofurea breath test in recurrent aphthous stomatitis patients was statistically higher than that of healthy controls.By these results we concluded that there was a correlation between recurrent aphthous somatitis and H.pyloriby using urea breath test in patients with recurrent aphthous stomatitis when compared with controls.]]>
