Context: Human T-cell lymphotropic viruses Type 1&2 (HTLV-1&2) screening test is endemic in someIraq’s provinces. HTLV-1&2 test is not performed in routine screening tests of Iraqi blood donors banks.With my thought it represent essential test to prevent complications the virus in our country and otherneighbour countries in Middle East. The results of the following study do not included all Iraq’s provincesbut only seven provinces (Baghdad, Karbala, Al-Qadisiyyah, Al-Najaf, Al-Muthanna, Al-Basrah, Wasit).Aims: to review prevalence of HTLV-1&2 infections among Iraq’s blood donors. Settings and Design:The study where performed in Iraqi National blood bank in Baghdad city and national companies forblood donation in Karbala and Najaf provinces, the study included 15239 blood donors. Methods andMaterial: ELISA (Murex HTLV 1&2 Ab, USA, LOT: D3101210) 480.T was used for HTLV screeningfor detection antibodies to HTLV-1&2 in the serum of human followed by accurate confirmatory testCMIA (Chemiluminescent microparticle immunoassay) architect plus for confirmatory. Results: The studyincluded 15239 blood donors, thirty nine of him appeared seropositive for HTLV-1&2, and the prevalenceof HTLV-1&2 was appeared in some provinces of Iraq country highly prevalence of HTLV-1&2 were seenin Baghdad 24(61.5%), then Karbala 5(12.8%), Al-Qadisiyyah 4(10.2%), Al-Najaf 2 (5.1%), Al-Muthanna2 (5.1%), Al-Basrah1(2.5%), and Wasit province1 (2.5%) respectively. Conclusions: first study conductedin Iraq in 2015 appeared the prevalence of HTLV-1&2 infections among blood donors only in six provincesand not included all Iraq’s provinces. So another study is requested for determination the distribution ofHTLV-1&2 in all Iraq’s provinces, districts and areas.