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All Journal Indian Journal of Forensic Medicine & Toxicology
Louay M. Alani1 , Huda M. Mahmood2 Bilal J. M. Aldahham3
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Heritability of Ambulatory Blood Pressure in Population of Western Region of Iraq Louay M. Alani1 , Huda M. Mahmood2 Bilal J. M. Aldahham3
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.11884

Abstract

Heritability of ambulatory blood pressure parameters in western population has been well described, thereis no information on Iraqi population. Therefore, the aim of the present study is to investigate geneticinfluences on intra-individual variation, by performing heritability analysis on an Iraqi population (Anbarprovince).A total of 389 individuals, constituting 93 families were ascertained. Most of the parents included in thestudy were in their 5th and 6th decade of life, and the siblings included in the study were in their 2nd and 3rddecade of life.To define the portion of difference of variables that is due to genetic and non-genetic influences, full sibanalysis was used to estimate heritabilities of blood pressure parameters systolic, diastolic, mean and pulsepressure were estimated during the morning and evening. Heritabilities were estimated in narrow sensewhich were ranged from 28 % for morning systolic blood pressure to 84% for morning systemic pulsepressure.The finding of modest narrow sense heritability indicates the significant role of non-genetic factors affectingmorning systolic, evening systolic and diastolic, and mean blood pressure, whereas the high estimate ofheritability for morning diastolic and pulse pressure indicate the significant effect of genetic.
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