Article Per Year (5 Year)
p-Index From 2021 - 2026
0
P-Index
This Author published in this journals
All Journal Indian Journal of Forensic Medicine & Toxicology
Poonam Madan1 , Bharat Rathi2 , Shailesh Nagpure3 , Raunak Kotecha
Unknown Affiliation
Public Health

Published : 1 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search

 1 
Experimental Evaluation of Talisadi Suspension for Anti-Histaminic and Anti-Inflammatory Activities in Animal Models Poonam Madan1 , Bharat Rathi2 , Shailesh Nagpure3 , Raunak Kotecha
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.12629

Abstract

Talisadichoorna is a routinely used formulation among ayurvedic practitioner in disorder of Pranavaha,Annavaha and Rasavahastrotasvyadhi’s. As choorna has some drawbacks, as a dosage forms talisadichoornawas converted into a modern dosage form i.e. suspension. It is better than choorna in aspects like ease inadministration, longer shelflife and faster absorption. Standard Operating Procedure was followed for itspreparation. No work was reported regarding its pharmacological action except for anti microbiologicalstudy.This study aimed to assess its anti inflammatory and antihistaminic actions, which is clinically seen. Thisstudy helped in assessing mode of action of the formulation. The disease Tamak shwas can be correlatedwith Bronchial Asthma on the basis of pathology, signs and symptoms. Bronchial Asthma is characterisedby dyspnoea, excessive cough, wheeze, chest tightness etc caused by airway inflammation and increasebronchial responsiveness. To study antiinflamtoamry activates model selected was “Granuloma pouchmodel” using rats as experimental animals. To study antihistaminic activity experimental animal guinea pigwas used and model used was “Protection against histamine induced brochospasm model”. It was evidentthat Talisadi Suspension exhibit significant anti-inflammatory and antihistaminic activities.
Co-Authors