Sura Zeki Salih1 , Mutaz S. Ahmied2 , Israa H. Abdulkareem2
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Evaluation of Serum Level of Serum Catalase and SOD as a Predictive Factors in Preterm Labor Patients Sura Zeki Salih1 , Mutaz S. Ahmied2 , Israa H. Abdulkareem2
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.12720

Abstract

The study is a comparative case control study conducted on 45 preterm delivery between (28-37 week)of gestation as cases group and 45 term delivery between (37-42 week) of gestation as control group, atobstetrical and gynecology department of Salah Alden general hospital in Salah Alden city from 20th ofNovember 2019 to 15th February 2020. The blood sample taken from participated women and the oxidativestress parameter (F2-8-isoprostan and protein carbonyl) was measured by ELISA technique. The cases wereSingle and twin pregnancy with cervical dilatation >3 cm and fully effaced cervix, and/or rupture membrane,Uterine contraction 3per 10 min and Indicated labor pregnancy like bleeding, DM, hypertension, pPROM,fetal destress, fetal death. But uncertain gestational age, elective term cesarean section, liver disease, renaldisease and hepatitis infected women were excluded.Result: Mean age of participants was (26.05±6.59 years) with a range of (14-45years) and mean weight was(74.84±6.728 Kg), range of (60-95 Kg) and mean height of participated (156.14±5.3 cm) and range of (150-170 cm).Superoxide dismutase and catalase showed significant decrease in preterm labor (mean±standererror) (529.161 ± 35.87 U/ml) (1.637 ± 0.12 pg/ml) respectively in compare with (mean± stander error)(1.637± 0.12U/ml) (529.161± 35.87 pg/ml) in preterm labor.Conclusion: This study showed that catalase and superoxide dismutase significantly decrease in pretermlabor group.