Rekha V Shinde1 , Ranjit Ambad2 , Pradip Adhav,3 Praful Fadanvis4 , Swarupa Chakole5
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Rasaushadhi (Herbomineral Formulations) Induced Nephrotoxicity in Children: Safety Concern Case Series Rekha V Shinde1 , Ranjit Ambad2 , Pradip Adhav,3 Praful Fadanvis4 , Swarupa Chakole5
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.12741

Abstract

Background: Use of Rasaushadhi (Herbomineral formulations) in children is sensible topic. In last decade,some articles reported in various newspapers about nephrotoxicity of Ayurvedicherbomineral medicines.These issues create negative impression regarding the use of Ayurvedicherbomineral medicines. Ayurvedaitself a time tested life science and provide guidelines to stay healthy and preserve the health. Such articleshave done considerable damage to the reputation of ayurveda but at same time, it has raised many questionswhich need to be addressed. To make system more scientific and evidence based study was conducted atPaediatric department of Government institute in 2017. Paediatric department in this institute has usedRasaushadhi in children several times and not noted any problem regarding nephrotoxicity till date.Aim: Question: Does Rasaushadhi (Herbomineral formulations) cause Nephrotoxicity in children? Todetermine Rasaushadhi (Herbomineral formulations) is “safe” study was conducted.Materials and Method: Study was conducted for recurrent and reactive respiratory illness in children andherbomineral five drugs regimen was given to children of age 4 to 14 years for 45 days at 15 days interval.To rule out Nephrotoxicity after the use of Ayurvedicherbomineral formulations kidney function test wasdone. Patients were clinically observed in 4 follow ups, each follow up was conducted every 15 days. Last(Fourth) telephonic follow up was taken after six months of completion of treatment course to observe anyrenal obstructive pathology.Results: Total 13 patients of case series were observed normal kidney function test reports. Last (Fourth)telephonic follow up was also reported normal, no any renal complications reported.Conclusion: This clinical case series found that use of Ayurvedicherbomineral medicines in paediatricpatients is safe and there is no relation with nephrotoxicity or any obstructive renal pathology when usedproperly