Ranjit S. Ambad1, Mihika Suryawanshi2, Rakesh Kumar Jha3, Pankaj D. Mulchandani2, Sudhir Singh4
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To Assess the Serum Vitamin D in Vitiligo Patients: SMHRC and AVBR Hospital of Vidarbha Region Ranjit S. Ambad1, Mihika Suryawanshi2, Rakesh Kumar Jha3, Pankaj D. Mulchandani2, Sudhir Singh4
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.12769

Abstract

Introduction: Vitiligo is a long-term skin condition that is characterized by skin patches which lose theirpigment. The affected skin patches are becoming white and typically have narrow margins. The skin haircan also turn white. Mouth and nose inside might also be involved. Occasionally, the vitiligo “comes infamilies,” implying a genetic origin. It ensures that the risk of other family members contracting vitiligois not predictable. Approximately 25 to 50 per cent of people with vitiligo have a parent with vitiligo, andaround 6 per cent have vitiligo siblings. Low serum levels of vitamin D have been associated with manyautoimmune disorders and a number of other skin conditions. Vitiligo is an autoimmune disease which ischaracterized by immune processes that kill melanocytes. Melanocytes express vitamin D receptors, andvitamin D status can affect their function.Objective: To assess serum Vit-D levels of vitiligo patients and contrast the outcomes and controls.Material and Method: In all out, 50 vitiligo patients and 50 controls were taken on the examination.Vit-D levels were estimated from blood tests. Gathering correlations were performed utilizing fitting factualstrategies.Observation and Results: The patients had lower serum Vit-D levels than the controls, yet this distinctionwas not noteworthy (p = 0.570).Conclusion: It stays obscure whether Vit-D inadequacy causes vitiligo. Bigger controlled investigations arerequired to demonstrate whether low flowing VIT-D is a causative factor in vitiligo.