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All Journal Indian Journal of Forensic Medicine & Toxicology
Kamola A. Sattarova1, Farida M. Ayupova2, Dilnoza D. Saidjalalova3, Dildora A. Ayupova4, Irina S. Akperbekova5, Firuza B. Mirodilova6
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Public Health

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Clinical and Biological Importance of Micro RNA in the Formation of Women Reproductive Losses Kamola A. Sattarova1, Farida M. Ayupova2, Dilnoza D. Saidjalalova3, Dildora A. Ayupova4, Irina S. Ak
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.12808

Abstract

Habitual miscarriage is currently one of the most frequent complications of the gestational process, whichis diagnosed in 10-25% of pregnant women. (IuA, 2017) Habitual abortion (miscarriage) - spontaneousinterruption of pregnancy two or more times in a row.So, high expression of miR133a may mediate a decrease in HLA-G expression at the protein level andmay be implicated in the pathogenesis of habitual miscarriage, since HLA-G provides immune tolerance inpregnancy49. So, the literature data suggest that microRNA dysregulation may be related to the pathogenesisof various obstetric complications, but accurate methodological approaches to the diagnosis and predictionof pregnancy complications using microRNA require further study.
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