<![CDATA[Oral squamous cell carcinoma is frequently occurring malignant tumour of the H & N (head and neck)region; with a rising oral cancer burden despite attempts of prevention, delay in diagnosis leads to locoregional spread and poor prognosis. Hence there is an utmost need for biomarkers which could lead to earlydiagnosis of oral carcinoma. In the quest for innovative and early diagnostic aid, liquid biopsy is evolvingas animportant tool in diagnostic oncology. A liquid biopsy also called a dynamic biopsy or fluid phasebiopsy is a non-invasive analysis of non-solid biological tissue predominantly blood. Malignant tumoursrelease different biomolecules into body fluids that have the potential to be used as biomarkers for diagnosis,prognosis, and therapy selection. As the clinical application of Circulating tumour DNA (ctDNA), circulatingtumour cells (CTCs), & exosomal miRNAs are quite significant they have acknowledged colossal attentionhave acknowledged gigantic consideration. Evaluation of the circulating biomarkers has made it easy forunique therapeutic methodologies and meticulous medicine. An increasing amount of studies have indicatedthat application of these biomarkers intended for detecting, therapeutic scheduling, reaction observing andprognosis management. Even though these novel biomarkers can deliver widespread series of conceivableclinical applications yet there arenot any authenticated circulating biomarkers which have been unified intothe clinical practice for oral carcinomas. This article is a brief review of the various biomarkers used inliquid biopsy as well as about tumour educated platelets.]]>
