<![CDATA[Corona virus disease -19(COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARSCoV2). Primarily it causes respiratory illness in humans. The pandemic caused by ths virus started in 2019in Wuhan , China. Later it was declared as pandemic by WHO. In this article I am reviewing the coronavirusalong with its microbilogical structure, transmission, pathogenesis, clinical features and its management.The virus is a singl stranded RNA virus. The virus enters the respiatory tract via mucous membrane ofmouth or nose. It binds to ACE TYPE 2 receptor and causes alveolar edema and its destruction leading todecrease in gas exchange which further leads to hypoxaemia finally leading to acute respiratory distresssyndrome ( ARDS). It most patients COVID19 presents with mild symptoms and they doesn’t require anymedical intervention. But patietnts presenting with severe symptoms needs vigilant medical attention andmay require ventilatory support. Most common symptoms are fever, dry cough, shortness of breath, fatigue, nasal congestion. The infection spreads via droplet from an infected person. Infection with this virusmay lead to severe inflammatory response leading to release of cytoines which causes increased capillarypermeability and vasodilatation leading to hypotension which further leads to decrease in blood supplyto multiple organs leading to multiple organ failure. There is increase chances of morbidity and mortalityamong elderly and in those with comorbidities. In eldrely the chance of fatality is way more than youngpeople. No one drug has been found yet as the ultimate treatment of COVID-19. Many drugs are underclinical trial and researches are going on for vaccine as well. But untill we get a definitive cure the onlyescape we have is prevention and the only means to do that is to practice social distancing , proper handhygiene and sanitation.]]>
