Komal Shah1 , Deepika Singhal2 , Ashka Patel3 , Binita Gadhavi4 , Jay Karan5 , Abhay Gaidhane6 , Deepak B Saxena7
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Dry eye Disease During COVID-19 : Need for Investment Into Research to Develop Solutions? Komal Shah1 , Deepika Singhal2 , Ashka Patel3 , Binita Gadhavi4 , Jay Karan5 , Abhay Gaidhane6 , Dee
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 1 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i1.13441

Abstract

Purpose: To review the Clinical Trial Registry of India (CTRI) for clinical trials registered for theinterventions for the treatment of dry eye disease.Methods: CTRI was manually searched by using the different key words related to the dry eye. Trialsregistered after 2009 were included in the analysis. All the parameters like type of interventions, phase oftrial, sample size etc of the each trial were extracted in the predesigned proforma. Descriptive statistics wasreported in the form of frequency and percentages.Results: Total 35 trials were registered since 2010. Majority were phase 4 trials (Post Marketing Surveillance).More than half of the registered trials were related to the ayurvedic products. Most frequent allopathicintervention was lubricant and most frequently used comparator was Carboxy Methyl Cellulose. Range ofsample size in different trials was 30-300.Conclusion: A good number of trials related to the ayurvedic drugs are registered for dry eye. There is aneed for similar research efforts for allopathic interventions.