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All Journal Indian Journal of Forensic Medicine & Toxicology
Fatimah Kadhim Ibrahim AL- Mahdawi1 , Ali Shalash Sultan2 , Nabeel Khalid Mohamed Ali AL-Wandi3 , Mazin Razooqi Mohammed4 , Hayder Abdulhafdh Kurji5
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Evaluations of Inflammatory Status in Chronic Renal Failure Patients Undergoing Hemodialysis and Conservative Treatment Fatimah Kadhim Ibrahim AL- Mahdawi1 , Ali Shalash Sultan2 , Nabeel Khalid Mohamed Ali AL-Wandi3 , Ma
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 1 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i1.13808

Abstract

Introduction: - Chronic inflammation is a basic feature of end stage kidney disease and is associated withincreasing risk of mortality and morbidity in patients undergoing dialysis.The aim: - the study amid toevaluate white blood cells and IL-6 in patients undergoing hemodialysis and without hemodialysis. Methodsand Subjects:- The study was designed on 106 patients with chronic renal failure age range (20-69years).The patients divided in two groups according to treatment, 40 patients with conservative treatment and66 patients with hemodialysis treatment. IL-6 were determined by using a commercially available ELISAMicro wells kit. Total white blood cells count and differential count were determined by using an automatedhematology autoanlyzer XT2000i. Results:- showed a significant (p<0.05) decrease of total white bloodcells count, neutrophils, lymphocytes, monocytes, eosinophils and basophils in hemodialytic group whencompared with conservative group. But IL-6 levels was higher significantly (p<0.01) in hemodialytic groupwhen compared with conservative group. Conclusion: - hemodialysis session impaired immune system andactivated anti-inflammatory factors.
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