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All Journal Journal of Clinical Microbiology and Infectious Diseases
Tanaya, Putu Wahyu Dyatmika
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Immunology & microbiology

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Congenital neurosyphilis in neonatal sepsis by Leclercia adecarboxylata: a case report Tanaya, Putu Wahyu Dyatmika; Manuaba, Ida Ayu Sri Kusuma Dewi; Saputra, I Wayan Agus Gede Manik
Journal of Clinical Microbiology and Infectious Diseases Vol. 3 No. 2 (2023): Available online: December 2023
Publisher : Indonesian Society for Clinical Microbiology (Perhimpunan Dokter Spesialis Mikrobiologi Klinik Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/jcmid.v3i2.54

Abstract

Introduction: Sepsis remains a leading cause of morbidity and mortality in neonates. In accordance with the development of diagnostic testing, various pathogens have been found to cause neonatal sepsis, ranging from common to even rarer pathogens. Leclercia adecarboxylata is a Gram-negative bacillus rarely found in neonatal sepsis and was previously found predominantly in environmental settings and the human gastrointestinal tract as commensal bacteria. We describe a rare case of Leclercia adecarboxylata in neonatal sepsis with congenital neurosyphilis. Case Description: We present a male neonate born from a positive syphilis serological test mother, presented with sepsis manifestation. Blood culture reveals growth of Leclercia adecarboxylata. The patient received both therapeutic regimens of antibiotics for sepsis and congenital syphilis. The cerebrospinal fluid analysis also performed revealed suggestive of congenital neurosyphilis. The patient passed away due to multiple organ failure. Conclusion: Neonatal sepsis and congenital neurosyphilis present with identical manifestations; therefore, appropriate recognition and comprehensive management should be done
Co-Authors Manuaba, Ida Ayu Sri Kusuma Dewi Saputra, I Wayan Agus Gede Manik