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Hepatitis B pada Kehamilan: Strategi Pengabdian Masyarakat untuk Pencegahan dan Penanganan Moelyadi, Felly; Saraswati, Faizah Alda; Bulandaru, Favan Maulana; Husodo, Febrianto Adi; Samudra, Ferizal Negeri
Jurnal Pengabdian Masyarakat: Humanity and Medicine Vol 6 No 2 (2025): Jurnal Pengabdian Masyarakat: Humanity and Medicine
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/Hummed.V6I2.216

Abstract

Hepatitis B remains a major global health issue, particularly in pregnancy due to the high risk of vertical transmission from mother to baby. This type of transmission is a leading cause of chronic infection in infants and may result in long-term health consequences. This community engagement program was conducted at Haji General Hospital Surabaya to increase awareness among pregnant women and their families regarding the prevention, early detection, and management of Hepatitis B during pregnancy. The program utilized interactive educational methods, including presentations, the distribution of informative leaflets, and question-and-answer sessions. Participants’ knowledge was assessed before and after the sessions. Results demonstrated a significant increase in participants’ understanding of the definition, transmission modes, symptoms, and risk factors, as well as preventive and management strategies related to Hepatitis B in pregnancy. This initiative had a positive impact on raising awareness about the importance of screening, vaccination, and other preventive measures to reduce the risk of infection in pregnant women and their newborns. Such programs are expected to be carried out regularly to effectively lower the rate of perinatal Hepatitis B transmission in the community.
Investigating the Prognostic Value of Serum Albumin Levels in Patients Undergoing Hemodialysis: A Systematic Review and Meta-analysis Adrya, Jessica; Sasongko, Calvin; Andrean, Melvin; Kartadinata, Muhammad Faishal; Theis, Aveline Maisie; Putri, Syafira Ayudiah Syah; Mukti, A. Muh. Yasser; Moelyadi, Felly; Varsha, Srigita; Dhika, Veriantara Satya
Medicinus Vol. 15 No. 1 (2025): October
Publisher : Fakultas Kedokteran Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/med.v15i1.10770

Abstract

Background: Hypoalbuminemia, characterized by low serum albumin levels, is frequently observed in patients undergoing hemodialysis and has been identified as a potential predictor of increased mortality risk. This systematic review aims to evaluate the relationship between hypoalbuminemia and mortality in hemodialysis patients, assessing the prognostic value of serum albumin levels as an indicator for patient outcomes. Methods: A comprehensive search was conducted in databases including PubMed, Europe PMC, and Scopus to identify relevant studies. Studies were included if they investigated the association between serum albumin levels and mortality outcomes in adult patients undergoing hemodialysis. Data extraction was performed independently by two reviewers, focusing on study characteristics, patient demographics, albumin levels, and mortality outcomes. Quality assessment of studies was conducted using the Newcastle-Ottawa Scale (NOS). Result: A total of eight studies, encompassing 45,178 hemodialysis patients with a mean age in the 50s, met the inclusion criteria. The studies had a combined male cohort of 22,501 individuals. The definition of hypoalbuminemia varied across studies, with cutoff values ranging from 3.0 to 3.9 g/dL. Follow-up durations spanned from as early as 3 months to a maximum of 6.1 years. The meta-analysis revealed a pooled hazard ratio (HR) of 1.08 (95% CI: 0.94–1.25), suggesting a non-significant association between hypoalbuminemia and increased mortality risk (P = 0.28). However, substantial heterogeneity was present (I² = 79%), indicating variability across studies. Conclusions: Hypoalbuminemia showed a non-significant association with mortality in hemodialysis patients, though variability across studies suggests further research is needed for clarity.