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Persistence Detection of Sars-Cov-2 RNA in Healthcare Workers with COVID-19: A Case Report Jum Ahmad, Ilzy; Mulyo, Sostro; Ikram Hasanuddin, Abdi Dzul
Green Medical Journal Vol 2 No 3 December (2020): Green Medical Journal
Publisher : Fakultas Kedokteran Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/gmj.v2i3.63

Abstract

Coronavirus Disease 2019 (Covid-19) has now become a concern around the world. Until 6 September 2020, there were 190,665 cases in Indonesia, and it was in the third rank of most cases in the Asian region. It is important to determine the criteria of return to work for healthcare workers with Covid-19 positive in Indonesia. This case report discussed a female patient, 32 years old with chief complaint of fever and itchy throat since 2 days ago. She is a health care worker in the hospital, with a history of treating patients with positive confirmation of Covid-19 for 2 days in the ordinary ward before the case was confirmed with a history of contact approximately 5 days ago. The patient was diagnosed with positive confirmation of Covid-19 and was required for self-isolation. The patient still had positive results of RT-PCR Covid-19 up to the third examination in 30 days after the initial RT-PCR testing, although received specific antiviral treatment with oral oseltamivir and oral supplementation. Based on growing evidence that Sars-Cov-2 may not infectious for more than ten days in the mild-moderate disease, this case report is strengthening the use of symptom-based strategic approach to determine when to return to work in Indonesian healthcare workers with positive COVID-19.
Transfusi Trombosit Profilaksis pada Demam Berdarah Dengue : Bermanfaat atau Merugikan ? Mulyo, Sostro
Cermin Dunia Kedokteran Vol 42, No 12 (2015): Dermatologi
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (243.204 KB) | DOI: 10.55175/cdk.v42i12.940

Abstract

Komplikasi perdarahan masih menjadi penyebab kematian terbanyak kasus demam berdarah dengue (DBD). Meskipun trombositopenia bukan prediktor terhadap kejadian perdarahan pada kasus DBD tetapi masih menimbulkan kekhawatiran. Kontroversi sampai saat ini apakah transfusi trombosit profilaksis bermanfaat atau justru merugikan.Severe bleeding is still the largest causes of death in dengue hemorrhagic fever (DHF). Although thrombocytopenia is not a predictor of the incidence of bleeding in dengue cases but still raises clinicians’ concerns. The controversy is whether prophylactic platelet transfusion may be beneficial or detrimental.
Kardiomiopati Sirosis – Diagnosis dan Tatalaksana Mulyo, Sostro
Cermin Dunia Kedokteran Vol 44, No 1 (2017): Nutrisi
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (352.517 KB) | DOI: 10.55175/cdk.v44i1.807

Abstract

Kardiomiopati sirosis (KS) merupakan komplikasi kardiovaskuler sirosis hati yang jarang terdiagnosis, karena biasanya asimptomatik dan belum ada baku emas untuk diagnosis pasti. Kriteria diagnosis KS adalah disfungsi sistolik dan atau disfungsi diastolik disertai abnormalitas elektrofisiologi dan peningkatan biomarker molekuler. Penanganan farmakologis masih terbatas dan pilihan terbaik adalah transplantasi hati.Cirrhotic cardiomyopathy (CCM) is a cardiovascular complication of liver cirrhosis that is often underdiagnosed because usually is asymptomatic and do not have diagnostic gold standard. Diagnostic criteria for CCM are systolic and or diastolic dysfunction with electrophysiological abnormalities and increased molecular biomarkers. Pharmacological treatment is limited and the best option is liver transplantation. 
Profilaksis Primer Perdarahan Vaerises Gastroesofagus pada Sirosis Hati: Peranan Penghambat Beta Mulyo, Sostro
Cermin Dunia Kedokteran Vol 43, No 12 (2016): Kardiovaskular
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (896.798 KB) | DOI: 10.55175/cdk.v43i12.903

Abstract

Perdarahan varises gastroesofagus merupakan komplikasi utama pasien sirosis hati dengan mortalitas tinggi; oleh karena itu dibutuhkan profilaksis primer. Penghambat β non-selektif adalah salah satu modalitas terapi farmakologik yang direkomendasikan. Meskipun terbukti efektif mencegah kejadian pertama perdarahan, obat ini tidak dapat diberikan pada semua kondisi sirosis hati.Gastroesophageal varices bleeding is the most important complication in cirrhosis with high mortality; hence, primary prophylaxis is needed. Non-selective β blocker is one of the recommended pharmacotherapy to effectively prevent the first bleeding event, but its use can’t be generalized to all cirrhosis.